The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen.
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Summary
Previous reports suggesting that within 2 hr of an inflammatory stimulus, macrophages produce a monokine that acts systemically to alter body temperature, activate T cells, and induce hepatic protein synthesis of acute-phase reactants are supported.
- Type
- article
- Published
- 1981-09-01
- Cited by
- 205
- References
- 35
- OpenAlex
- https://openalex.org/W2012918825
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:41163331
Keywords
Monokine, Inducer, Endogeny, Lipopolysaccharide, Biology
References
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Cited by
- The Numerous Postulated Biological Manifestations of Interleukin‐1
- Chemical characterization of a rabbit leukocytic pyrogen.
- Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein.
- Generation of an interleukin-I-like lymphocyte-stimulating factor at inflammatory sites: correlation with the infiltration of polymorphonuclear leucocytes.
- Regulation of cytokine release from peritoneal macrophages of patients on continuous ambulatory peritoneal dialysis
- Corneal epithelial cell--derived thymocyte-activating factor (CETAF).
- The role of macrophages in the acute phase SAA response to endotoxin
- Neural responses to antigenic challenges and immunomodulatory factors.
- Serum amyloid A gene expression and AA amyloid formation in A/J and SJL/J mice.
- Monocyte interleukin-1 secretion is regulated by the sequential action of gamma-interferon and interleukin-2 involving monocyte surface expression of interleukin-2 receptors.
- Immunology in drug research.
- Different regulatory mechanisms for serum amyloid A and serum amyloid P synthesis by cultured mouse hepatocytes.
- Enhancement of glomerular mesangial cell neutral proteinase secretion by macrophages: role of interleukin 1.
- Sulphydryl-dependent reactions of D-penicillamine : pharmacokinetics and effects on monocyte function in rheumatoid arthritis
- Further comparisons of endogenous pyrogens and leukocytic endogenous mediators
- Amyloidosis and the serum amyloid A protein response to muramyl dipeptide analogs and different mycobacterial species
- Increased thymocyte-activating factor in human gingival fluid during gingival inflammation
- Thermal injury-induced expression of acute-phase proteins in rat liver.
- Induction of rat α2‐macroglobulin in vivo and in hepatocyte primary cultures: synergistic action of glucocorticoids and a Kupffer cell‐derived factor
- The effects of high-dose UV exposure on murine Langerhans cell function at exposed and unexposed sites as assessed using in vivo and in vitro assays.
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