Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells.
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Summary
A novel protein LYsine-RIch CEACAM1 co-isolated (LYRIC) that is widely expressed and highly conserved between species is described, which suggests that LYRIC is recruited during the maturation of the tight junction complex.
- Type
- article
- Published
- 2004-10-15
- Cited by
- 115
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W2000378520
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36845465
Keywords
Tight junction, Biology, Cell biology, Occludin, Septate junctions
References
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- Possible Involvement of Phosphorylation of Occludin in Tight Junction Formation
- The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction
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- Protein Kinase C Regulates the Phosphorylation and Cellular Localization of Occludin*
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Cited by
- The Role of AEG-1/MTDH/LYRIC in the Pathogenesis of Central Nervous System Disease
- AMPK inhibits MTDH expression via GSK3β and SIRT1 activation: potential role in triple negative breast cancer cell proliferation
- Caractérisation de l'ubinucléine, partenaire cellulaire du transactivateur ZEBRA du virus d'Epstein-Barr
- Expression of metadherin/AEG-1 gene is positively related to orientation chemotaxis and adhesion of human hepatocellular carcinoma cell lines of different metastatic potentials
- Nicotinic modulation of cerebral microvascular permeability
- Analysis of the Role of Astrocyte Elevated Gene-1 in Normal Liver Physiology and in the Onset and Progression of Hepatocellular Carcinoma
- Μοριακοί μηχανισμοί που εμπλέκονται στην ανεπάρκεια της αυξητικής ορμόνης
- AEG-1/MTDH/LYRIC: Signaling Pathways, Downstream Genes, Interacting Proteins, and Regulation of Tumor Angiogenesis
- Tight junctions: molecular architecture and function.
- The emerging role of astrocyte-elevated gene-1 in hepatocellular carcinoma (Review).
- Metadherin: An emerging key regulator of the malignant progression of multiple cancers
- AEG-1/MTDH/LYRIC, the Beginning: Initial Cloning, Structure, Expression Profile, and Regulation of Expression
- Cross-talk between tight and anchoring junctions-lesson from the testis.
- How does the oncogene astrocyte elevated gene-1 (AEG-1) augment glioma progression?
- Astrocyte Elevated Gene-1 (AEG-1) Regulates Lipid Homeostasis*
- AEG-1/MTDH/LYRIC: Clinical Significance
- Epigenetic Activation of TWIST1 by MTDH Promotes Cancer Stem-like Cell Traits in Breast Cancer.
- Genetic Ablation of Metadherin Inhibits Autochthonous Prostate Cancer Progression and Metastasis
- Engraftment of Syngeneic and Allogeneic Endothelial Cells, Hepatocytes and Cholangiocytes into Partially Hepatectomized Rats Previously Treated with Mitomycin C
- Astrocyte elevated gene-1: far more than just a gene regulated in astrocytes.
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