The polycomb group protein EZH2 is involved in progression of prostate cancer
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Summary
Dysregulated expression of EZH2 may be involved in the progression of prostate cancer, as well as being a marker that distinguishes indolent prostate cancer from those at risk of lethal progression.
- Type
- article
- Published
- 2002-10-10
- Cited by
- 2,760
- References
- 50
- Access
- Open access
- OpenAlex
- https://openalex.org/W1996487270
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4414767
Keywords
Prostate cancer, EZH2, Cancer research, Gene silencing, Cancer
References
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- Ectopic pharynxes arise by regional reorganization after anterior/posterior chimera in planarians.
- Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging.
- Heparan Sulfate Mediates bFGF Transport through Basement Membrane by Diffusion with Rapid Reversible Binding*
- Interference with brachyury function inhibits convergent extension, causes apoptosis, and reveals separate requirements in the FGF and activin signalling pathways.
- Chromatin silencing and activation by Polycomb and trithorax group proteins
Cited by
- Post-genomic applications of tissue microarrays: basic research, prognostic oncology, clinical genomics and drug discovery.
- The interferon-inducible p200 family of proteins: a perspective on their roles in cell cycle regulation and differentiation.
- Update of staging and risk assessment for prostate cancer patients
- Genes differentially expressed in prostate cancer
- Akt-Mediated Phosphorylation of EZH2 Suppresses Methylation of Lysine 27 in Histone H3
- Defining aggressive prostate cancer using a 12-gene model.
- Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer
- Androgen regulation of soluble guanylyl cyclaseα1 mediates prostate cancer cell proliferation
- DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.
- Histone modifications as markers of cancer prognosis: a cellular view
- The emerging functions of histone demethylases.
- Overexpression of metastasis-associated MTA1 in oral squamous cell carcinomas: correlation with metastasis and invasion.
- GOLPH2 protein expression as a novel tissue biomarker for prostate cancer: implications for tissue-based diagnostics
- Metastasis: from dissemination to organ-specific colonization
- Epigenetic Deregulation Across Chromosome 2q14.2 Differentiates Normal from Prostate Cancer and Provides a Regional Panel of Novel DNA Methylation Cancer Biomarkers
- The SNP rs6441224 influences transcriptional activity and prognostically relevant hypermethylation of RARRES1 in prostate cancer
- Nuclear Morphometry, Epigenetic Changes, and Clinical Relevance in Prostate Cancer
- Linking the SWI/SNF complex to prostate cancer
- Specific protein markers for stem cell cross-talk with neighboring cells in the environment.
- Altered histone modifications in cancer.
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