Modulation of the efficiency of a siRNA directed against MDR1 expression in MCF7-R cells when combined with a second siRNA.

Keywords

Small interfering RNA, Gene silencing, Transfection, Trans-acting siRNA, RNA interference

References

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• Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells.Zhenfeng Duan, Katherine A. Brakora, Michael V. Seiden — 2004
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• Strategies for inhibition of MDR1 gene expression.Xu D, Hyun Min Kang, Michael H. Fisher — 2004
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• Small RNA asymmetry in RNAi: Function in RISC assembly and gene regulationGyörgy Hutvágner — 2005
• Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi)Christiane Nieth, Axel Priebsch, A. Stege — 2003
• Functional siRNAs and miRNAs exhibit strand bias.Anastasia Khvorova, Angela Reynolds, Sumedha D. Jayasena — 2003
• TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencingThimmaiah P. Chendrimada, Richard I. Gregory, Easwari Kumaraswamy — 2005
• Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells.Hao Wu, William N. Hait, Jin-Ming Yang — 2003
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• The Reduction of P-Glycoprotein Expression by Small Interfering RNAs Is Improved in Exponentially Growing CellsVérène Stierlé, Alain Laigle, Béatrice Jollès — 2004
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• R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi PathwayQinghua Liu, Tim Rand, Savitha Kalidas — 2003
• Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes.Christian B. Matranga, Yukihide Tomari, Chanseok Shin — 2005
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Cited by

• ANTICANCER PROPERTIES OF RESEARCH-GRADE HYDRASTIS CANADENSIS (GOLDENSEAL) AND CHARACTERIZATION OF ITS EFFECT ON THE MDR1 -ENCODED PHOSPHOGLYCOPROTEIN EFFLUX PUMPSara Marie Garrett — 2009
• Évaluation de l'efficacité des nanoparticules chitosane-siARN à inhiber, in vitro, l'expression du gène MDR1 responsable de la résistance à la chimiothérapieMohamed Benhammadi — 2014
• Competition between small RNAs: a quantitative view.Adiel Loinger, Yael Shemla, Itamar Simon — 2012
• Dissecting Systemic RNA Interference in the Red Flour Beetle Tribolium castaneum: Parameters Affecting the Efficiency of RNAiSherry Miller, Keita Miyata, Susan J. Brown — 2012
• Competition potency of siRNA is specified by the 5'-half sequence of the guide strand.Jae Wook Yoo, Soyoun Kim, Dong-ki Lee — 2008
• Identification of sequence features that predict competition potency of siRNAs.Xin Li, Jae Wook Yoo, June Hyung Lee — 2010
• Reversal of multidrug resistance by small interfering RNA (siRNA) in doxorubicin-resistant MCF-7 breast cancer cells.Yaprak Dönmez Çakıl, Ufuk Gündüz — 2011
• Therapeutic potential of RNA interference in drug-resistant cancers.Hermann Lage — 2009
• Competition Between siRNA Duplexes: Impact of RNA-Induced Silencing Complex Loading Efficiency and Comparison Between Conventional-21 bp and Dicer-Substrate siRNAsMarcel Tanudji, Dorothy A. Machalek, Greg M. Arndt — 2010
• RNA interference in the red flour beetle Tribolium castaneumSherry C. Miller — 2009
• Recent attempts at RNAi‐mediated P‐glycoprotein downregulation for reversal of multidrug resistance in cancerMeysam Abbasi, Afsaneh Lavasanifar, Hasan Uludaˇ — 2013
• Cell-Penetrating, Guanidinium-Rich Molecular Transporters for Overcoming Efflux-Mediated Multidrug ResistanceJessica R. Vargas, Erika Geihe Stanzl, Nelson N.H. Teng — 2014

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