Tumour necrosis factor and lymphotoxin genes map close to H–2D in the mouse major histocompatibility complex
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Summary
Using polymorphic restriction sites to analyse a panel of MHC congeneic and intra-MHC recombinant mouse strains, it is found the TNF genes are located 70 kb proximal to the D gene.
- Type
- article
- Published
- 1987-01-15
- Cited by
- 203
- References
- 21
- OpenAlex
- https://openalex.org/W1992641263
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4357766
Keywords
Lymphotoxin, Lymphotoxin alpha, Major histocompatibility complex, Lymphotoxin beta receptor, Gene
References
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- Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization.
- Gene organization and recombinational hotspots in the murine major histocompatibility complex.
- The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse.
- Tracts of high or low sequence divergence in the mouse major histocompatibility complex.
Cited by
- Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages
- Tumor Necrosis Factor and Lymphotoxin: Molecular Genetics, Regulation and Physiological Role
- Is TNF beneficial or deleterious in toxoplasmic encephalitis?
- Lymphotoxins: from cytotoxicity to lymphoid organogenesis.
- Lymphotoxin's link to carcinogenesis: friend or foe? from lymphoid neogenesis to hepatocellular carcinoma and prostate cancer.
- Cytokine and free radicals as effector molecules in the destruction of pancreatic beta cells.
- Genetics of tumor susceptibility in the mouse: MHC and non-MHC genes.
- Biology and genetics of hybrid resistance.
- The common mediator of shock, cachexia, and tumor necrosis.
- Analysis and characterization of the swine major histocompatibility complex
- The role of class II molecules in development of insulin-dependent diabetes mellitus in mice, rats and humans.
- RFLP analysis in the TNF-beta gene and the susceptibility to alloreactive NK cells in Behçet's disease.
- Cytokines in degenerative brain diseases: lessons from transgenic animals.
- Tumor Necrosis Factor Alpha Converting Enzyme: An Encouraging Target for Various Inflammatory Disorders
- Cytokines and the initiation of parturition.
- Physical maps of the mouse and human immunoglobulin-like loci.
- CD40-CD40 ligand: a multifunctional receptor-ligand pair.
- A Novel Susceptibility Locus On Chromosome 2 in the (New Zealand Black × New Zealand White)F1 Hybrid Mouse Model of Systemic Lupus Erythematosus1
- Novel concepts of tumor necrosis factor action in autoimmune pathology.
- TNFB Gene Polymorphism in Patients with Systemic Lupus Erythematosus in Korean
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