On mammary stem cells
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Summary
A better understanding of the signal transduction pathways and the molecules that are responsible for the self-renewal and survival of these cells will be essential in the design of more effective therapies aimed at the eradication of both cancer-initiating cells and breast cancer stem cells.
- Type
- review
- Published
- 2005-08-15
- Cited by
- 138
- References
- 76
- OpenAlex
- https://openalex.org/W1989281114
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19920968
Keywords
Biology, Stem cell, Wnt signaling pathway, Mammary gland, Myoepithelial cell
References
- The segregation of DNA in epithelial stem cells.
- Stem cell origin of cancer and differentiation therapy.
- Hedgehog Signaling Pathway is a New Therapeutic Target for Patients with Breast Cancer
- Functional and molecular characterisation of mammary side population cells
- Beta-catenin and Tcfs in mammary development and cancer.
- Hedgehog acts as a somatic stem cell factor in the Drosophila ovary
- Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice.
- An Atlas of Mouse Mammary Gland Development
- A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland.
- Mutation selection and the natural history of cancer
- Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo
- Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors.
- WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type
- A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003.
- Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
- Sustained Loss of a Neoplastic Phenotype by Brief Inactivation of MYC
- Self-Renewal and Cancer of the Gut: Two Sides of a Coin
- Epithelial Progenitors in the Normal Human Mammary Gland
- Identification of human brain tumour initiating cells
- PTENless means more.
Cited by
- DNMT1 ablation suppresses tumorigenesis by inhibiting the self-renewal of esophageal cancer stem cells
- Regulación de la diseminación de los tumores sólidos murinos por el sistema del ácido retinoico y sus receptores
- Identification of drug-resistance predictive genes in breast cancer neoadjuvant chemotherapy
- Growth of mesenchymal stromal cells in automated microwell cultures : influence of the engineering environment on cell growth kinetics and non-directed differentiation
- Human Adipose-Derived Mesenchymal Stromal Cells May Promote Breast Cancer Progression and Metastatic Spread
- Genetic biomarkers as prognostic and predictive factors in metastatic malignant melanoma
- PREPARATION OF EPITHELIAL AND MESENCHYMAL STEM CELLS FROM MURINE MAMMARY GLAND
- Identify in Breast Cancer Stem Cell-Like Cells the Proteins Involved in Non- Homologous End Joining DNA Repair
- Das Stammzellkonzept der Mamma
- Targeting Breast Cancer Recurrence via Hedgehog-Mediated Sensitization of Breast Cancer Stem Cells
- Molecular regulation of breast cancer susceptibility by dietary factors
- Stem cells in human breast cancer.
- MicroRNA-200c-141 and ∆Np63 are required for breast epithelial differentiation and branching morphogenesis.
- Boss/Sev signaling from germline to soma restricts germline-stem-cell-niche formation in the anterior region of Drosophila male gonads.
- Cellular Quiescence in Mammary Stem Cells and Breast Tumor Stem Cells: Got Testable Hypotheses?
- Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation
- Epithelial to mesenchymal transition as a portal to stem cell characters embedded in gene networks.
- Image-guided sampling reveals increased stroma and lower glandular complexity in mammographically dense breast tissue
- Fat grafting and stem cell enhanced fat grafting to the breast under oncological aspects--recommendations for patient selection.
- KEGG-PATH: Kyoto encyclopedia of genes and genomes-based pathway analysis using a path analysis model.
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