Overexpression and Amplification of the c‐myc Gene in Mouse Tumors Induced by Chemicals and Radiations
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Summary
Tumor type specificity and agent specificity of c‐myc gene amplification are indicated and 8 cases of sarcomas induced by radiations, but could not find changes in the gene structure of the c‐ myc gene.
- Type
- article
- Published
- 1989-03-01
- Cited by
- 19
- References
- 26
- Access
- Open access
- OpenAlex
- https://openalex.org/W1987660851
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13720327
Keywords
Gene, Southern blot, Gene duplication, Gene expression, Biology
References
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- A closed cabinet system with water flushers and a blender for breeding small animal administered 3HHO.
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- Nucleotide sequence of the rightward operator of phage lambda.
- Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29
- Overreplication and recombination of DNA in higher eukaryotes: potential consequences and biological implications.
- onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient
- Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.
- Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas
- Detection of specific sequences among DNA fragments separated by gel electrophoresis.
- Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas.
- Proviruses are adjacent to c-myc in some murine leukemia virus-induced lymphomas.
- The complete sequence of a chromosomal mouse alpha--globin gene reveals elements conserved throughout vertebrate evolution.
- Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.
- Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.
Cited by
- Radiation induction of germline mutation at a hypervariable mouse minisatellite locus.
- Presence of point mutations in the N-ras gene in radiation-transformed rat embryo cells.
- Random Process of Metastasis and Generation of Heterogeneity in a Mouse Sarcoma Line
- Induction of Transplantable Tumors by Repeated Subcutaneous Injections of Natural and Synthetic Vitamin E in Mice and Rats
- Lack of Allelic Preference in Amplification and Loss of the c‐myc Oncogene in Methylcholanthrene‐induced Mouse Sarcomas
- Extrapolation of Radiation-Induced Cancer Risks from Nonhuman Experimental Systems to Humans
- Analysis of Clonal Evolution in a Tumor Consisting of pSV2neo‐transfected Mouse Fibrosarcoma Clones
- Oncogenes and radiation carcinogenesis.
- Somatic Mutation during Metastasis of a Mouse Fibrosarcoma Line Detected by DNA Fingerprint Analysis
- Analysis of transforming genes in indirectly induced radiogenic thymomas in mice.
- The N-ras proto-oncogene can suppress the malignant phenotype in the presence or absence of its oncogene.
- Complex effects of Ras proto-oncogenes in tumorigenesis.
- MUTATION ANALYSIS OF THE PROTO-ONCOGENES Ki-RAS AND C-MYC IN THE SOFT TISSUE TUMORS OF THE RATS THAT WERE FORMED BY 3-METHYLCHOLANTHRENE IN VIVO
- VITAMIN E AND CARCINOGENESIS
- Experimental Studies on Radiogenic Leukemia and Breast Cancer
- Phenotype in the Presence or Absence of Its Oncogene Proto-oncogene Can Suppress the Malignant ras The N-Updated
- D.P.Ü. Fen Bilimleri Enstitüsü Mutation Analysis of the Proto-Oncogenes Ki-Ras and C-MYC in the Soft Tissue Tumors
- General Characteristics of Tumor Viruses. Viral and Cellular Oncogenes. Nonviral Oncogene Activators
- Ionizing Radiation as a Carcinogen
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