Radiation induction of germline mutation at a hypervariable mouse minisatellite locus.
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Summary
The results suggest the presence of a previously unexpected mechanism of radiation induction of germline mutation and demonstrate that the hypervariable minisatellite locus can serve as a sensitive monitor for genetic damages to germline cells.
- Type
- article
- Published
- 1993-12-01
- Cited by
- 107
- References
- 24
- OpenAlex
- https://openalex.org/W2091078669
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:33023090
Keywords
Minisatellite, Biology, Germline, Locus (genetics), Genetics
References
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- Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA
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- Very low doses of X-rays can cause human lymphocytes to become less susceptible to ionizing radiation.
- Two mouse hypervariable minisatellites: chromosomal location and simultaneous mutation.
Cited by
- Current and future contributions of transgenic mice to the analysis of germline toxicology.
- Germline mutation induction at mouse and human tandem repeat DNA loci.
- Ionising radiation and mutation induction at mouse minisatellite loci. The story of the two generations.
- Germline DNA: Wheat mutation rate after Chernobyl
- Multi-side approach to the realities of the Chernobyl NPP accident : summing-up of the consequences of the accident twenty years after (II)
- Lack of effects of atomic bomb radiation on genetic instability of tandem-repetitive elements in human germ cells.
- Genetic studies at the Atomic Bomb Casualty Commission-Radiation Effects Research Foundation: 1946-1997.
- Radiation-induced genomic instability in Caenorhabditis elegans.
- Genetic effects of radiation in atomic-bomb survivors and their children: past, present and future.
- A single-molecule PCR approach to the measurement of induced expanded simple tandem repeat instability in vitro.
- Induction of germline‐length mutations at the minisatellites PC‐1 and PC‐2 in male mice exposed to polychlorinated biphenyls and diesel exhaust emissions
- The effects of extremely low frequency magnetic fields on mutation induction in mice.
- Environmental radiation and male reproduction.
- Elevated minisatellite mutation rate in the post-chernobyl families from ukraine.
- Two recent radiation-related genetic false alarms: leukemia in West Cumbria, England, and minisatellite mutations in Belarus.
- Radiation-induced genomic instability.
- The radiation-induced bystander effect: evidence and significance
- Very high mutation rate in offspring of Chernobyl accident liquidators
- Human minisatellite mutation rate after the Chernobyl accident
- Delayed effects and induction of genetic instability by radiation.
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