Macrophage polarization comes of age.
Explore this paper's citation graph
Summary
Functional polarization of macrophages into M1 or M2 cells is an operationally useful, simplified conceptual framework describing the plasticity of mononuclear phagocytes.
- Type
- review
- Published
- 2005-10-01
- Cited by
- 1,296
- References
- 14
- Access
- Open access
- OpenAlex
- https://openalex.org/W1986736465
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20578309
Keywords
Biology, Macrophage polarization, Immunology, Macrophage, Genetics
References
- Transcriptional Profiling Reveals Complex Regulation of the Monocyte IL-1β System by IL-131
- Some nuts are tougher to crack than others.
- Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology.
- Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes.
- Alternatively activated macrophages during parasite infections.
- Alternative activation of macrophages
- Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury.
- Blocking IL-1 in systemic inflammation
- SHIP represses the generation of alternatively activated macrophages.
- Acidic Mammalian Chitinase in Asthmatic Th2 Inflammation and IL-13 Pathway Activation
- The chemokine system in diverse forms of macrophage activation and polarization.
- Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair.
- Lipopolysaccharide-Induced Macrophage Inflammatory Response Is Regulated by SHIP1
- Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
Cited by
- Caracterització del tipus d'activació de diferents poblacions de macròfags durant la pancreatitis aguda experimental i la seva relació amb la severitat del procés
- Differential Macrophage Polarization in Male and Female BALB/c Mice Infected With Coxsackievirus B3 Defines Susceptibility to Viral Myocarditis
- Neuroinflammation responses and neurodegeneration in multiple sclerosis.
- REVIEW ARTICLE: The Contribution of Macrophages to Normal and Pathological Pregnancies
- Monocyte polarization: the relationship of genome-wide changes in H4 acetylation with polarization
- In Vitro and In Vivo Models of Cerebral Ischemia Show Discrepancy in Therapeutic Effects of M2 Macrophages
- A Computational, Tissue-Realistic Model of Pressure Ulcer Formation in Individuals with Spinal Cord Injury
- Footprints of Sepsis Framed Within Community Acquired Pneumonia in the Blood Transcriptome
- A fatal attraction: macrophage recruitment to the atherosclerotic plaque
- Cellular and molecular strategies to overcome macrophage-mediated axonal dieback after spinal cord injury
- Comparative models of transplant and non-transplant human kidney disease
- Serotonin modulation of macrophage polarization: inflammation and beyond.
- Interaction of monocytes with glomerular mesangial cell matrix in the pathogenesis of glomerular injury
- The interrelationship of strain diversity, virulence and patient ethnicity for tuberculosis in the Midlands, UK
- Defining Dendritic Cells and Macrophages in Lymph Nodes and Gut Mucosa During Simian Immunodeficiency Virus Infection
- An in vivo model system for evaluation of the host response to biomaterials.
- SOCS1/SOCS3 Expression and Virus Replication of DENV2 and HSV-1 in Cytokine-Polarized Subsets of RAW 264.7 Macrophages
- Modulation des cellules dendritiques et macrophages : implications dans le cancer et l'athérosclérose
- Decellularized matrices for cardiovascular tissue engineering.
- Role of macrophages in cardiac homeostasis and repair following myocardial infarction
Related papers
- Artificially induced in situ macrophage polarization: An emerging cellular therapy for immuno-inflammatory diseases.
- Macrophage Polarization in Atherosclerosis.
- LAIR-1 activation inhibits inflammatory macrophage phenotype in vitro.
- Multiple roles of macrophage in skin.
- Relationship between macrophage polarization and age-related macular degeneration
- Micro-RNAs and macrophage diversity in atherosclerosis: new players, new challenges…new opportunities for therapeutic intervention?
- Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?
- Targeting Macrophage Subsets for Infarct Repair
- The significance of M1 macrophage should be highlighted in peripheral nerve regeneration.