Induction of angiogenesis during the transition from hyperplasia to neoplasia
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Summary
It is reported here that angiogenic activity first appears in a subset of hyperplastic islets before the onset of tumour formation, suggesting that induction of angiogenesis is an important step in carcinogenesis.
- Type
- article
- Published
- 1989-05-04
- Cited by
- 1,972
- References
- 25
- OpenAlex
- https://openalex.org/W1985528986
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4366882
Keywords
Angiogenesis, Hyperplasia, Carcinogenesis, Cancer research, Biology
References
- Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons.
- The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. A quantitative histologic study.
- Cell turnover of capillaries.
- Proliferation, senescence, and neoplastic progression of beta cells in hyperplasic pancreatic islets.
- The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
- Tumor angiogenesis: therapeutic implications.
- Angiogenesis in vitro
- A possible mechanism for inhibition of angiogenesis by angiostatic steroids: induction of capillary basement membrane dissolution.
- Genetics of human cancer.
- Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes.
- An improved method for isolation of mouse pancreatic islets.
- Angiogenesis as a marker of preneoplastic lesions of the human breast
- Long-term culture of capillary endothelial cells.
- Oncogenes and growth control
- Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors.
- Angiogenic Activity as a Marker of Neoplastic and Preneoplastic Lesions of the Human Bladder
- The approaching era of the tumor suppressor genes.
- Transplacental carcinogenesis by stilbestrol.
- Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis.
- In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices
Cited by
- Preclinical Molecular Imaging of Tumor Angiogenesis
- The role of fibroblast growth factors and related oncogenes in tumor growth.
- Plasminogen activators and angiogenesis.
- Angiogenesis: models and modulators.
- Angiogenesis: a new diagnostic aspect of obstetric and gynecologic echography
- PROGNOSTIC SIGNIFICANCE OF MICROVESSEL COUNT IN LOW STAGE RENAL CELL CARCINOMA
- Expression of Vascular Endothelial Growth Factor-A and its Receptors in Uteroplacental Tissues of the Normotensive and Hypertensive Pregnant Rat
- A systems approach to cancer therapy
- Inhibitory effects of CAI in glioblastoma growth and invasion
- Clinical and molecular prognostic factors in sphincter-preserving surgery for rectal cancer.
- Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
- Applications of magnetic resonance in model systems: tumor biology and physiology.
- RESPONSE: re: initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models
- Cyclin D1, Retinoblastoma, p53, and Her2/neu Protein Expression in Preinvasive Breast Pathologies: Correlation with Vascularity
- Thalidomide as an Anti-angiogenic Agent in Relapsed Gliomas
- Suppression of tumor angiogenesis through the inhibition of integrin function and signaling in endothelial cells: which side to target?
- Inhibition of constitutive NF-κB activity by IκBαM suppresses tumorigenesis
- Mammary tumor fibroblasts are phenotypically distinct from non-tumor fibroblasts.
- Target validation using RNA interference in solid tumors.
- Ligand-Directed AAVP to Deliver a Therapeutic Transgene to Neuroendocrine Tumors of the Pancreas
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