Studies on the oridonin-loaded poly(D,L-lactic acid) nanoparticles in vitro and in vivo.
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Summary
The results of pharmacokinetics demonstrated that being encapsulated in PLA nanoparticles was remarkably effective for ORI to prolong its blood circulation time.
- Type
- article
- Published
- 2007-01-30
- Cited by
- 96
- References
- 17
- OpenAlex
- https://openalex.org/W1975963264
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44856908
Keywords
In vivo, Lactic acid, In vitro, Nanoparticle, Chemistry
References
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- Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D, L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior.
- Lidocaine-loaded biodegradable nanospheres. I. Optimization Of the drug incorporation into the polymer matrix.
- Thermoanalysis of microspheres
- Solid-state characterization of nifedipine solid dispersions.
- The effect of spray drying solutions of bendroflumethiazide/polyethylene glycol on the physicochemical properties of the resultant materials.
- Biodegradable polymeric nanoparticles as drug delivery devices.
- Antibacterial trichorabdal diterpenes from Rabdosia trichocarpa.
- PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug.
- Preparation of aqueous polymeric nanodispersions by a reversible salting-out process : influence of process parameters on particle size
- Comparison of the mechanical properties of the crystalline and amorphous forms of a drug substance.
- Polymeric systems for controlled drug release.
- Cytotoxic and antitumor activities of Rabdosia diterpenoids.
- Characterization and release of triptolide-loaded poly (D, L-lactic acid) nanoparticles
- Biodegradable nanoparticles for drug and gene delivery to cells and tissue.
- Long-circulating and target-specific nanoparticles: theory to practice.
- Preparation of poly(DL-lactide-co-glycolide) nanoparticles by modified spontaneous emulsification solvent diffusion method.
Cited by
- Influence of process and formulation parameters on the formation of submicron particles by solvent displacement and emulsification-diffusion methods critical comparison.
- Preparation and Characterization of Poly(Lactic Acid) Nanoparticles for Pharmaceutical Use
- Amphiphilic polylactic acid‐hyperbranched polyglycerol nanoparticles as a controlled release system for poorly water‐soluble drugs: physicochemical characterization
- Encapsulation of podophyllotoxin and etoposide in biodegradable poly-d,l-lactide nanoparticles improved their anticancer activity
- An HPLC method for determination of oridonin in rabbits using isopsoralen as an internal standard and its application to pharmacokinetic studies for oridonin-loaded nanoparticles.
- Release profile characteristics of biodegradable-polymer-coated drug particles fabricated by dual-capillary electrospray.
- Tumor accumulation of NIR fluorescent PEG-PLA nanoparticles: impact of particle size and human xenograft tumor model.
- Designing polymeric microparticulate drug delivery system for hydrophobic drug quercetin
- Biosurfactant stabilized anticancer biomolecule-loaded poly (D,L-lactide) nanoparticles.
- An improved HPLC method with fluorescence detection for the determination of pyrene in rat plasma and its pharmacokinetics.
- Oridonin suppresses transplant rejection by depleting T cells from the periphery.
- Preparation, physicochemical characterization, and antioxidant effects of quercetin nanoparticles.
- Therapeutic efficacy and toxicity of tamoxifen loaded PLA nanoparticles for breast cancer.
- Preparation of aqueous crosslinked dispersions of functionalized poly(d,l-lactic acid) with a thermomechanical method
- Chitosan-g-poly(N-isopropylacrylamide) based nanogels for tumor extracellular targeting.
- In vivo studies on the oridonin-loaded nanostructured lipid carriers
- Galactose-decorated pH-responsive nanogels for hepatoma-targeted delivery of oridonin.
- Development of biodegradable nanoparticles for delivery of quercetin.
- Review of Nanobiopolymers for Controlled Drug Delivery
- Preparation and Evaluation of β-TCP /Polylactide Microspheres as Osteogenesis Materials
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