Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein.
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Summary
These and related findings support the idea that GAL4 activates transcription by touching other DNA-bound proteins.
- Type
- article
- Published
- 1986-02-14
- Cited by
- 578
- References
- 34
- OpenAlex
- https://openalex.org/W1975712471
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:206577893
Keywords
Transcription (linguistics), Repressor, Transcription factor, Eukaryotic transcription, DNA
References
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- Molecular expression and regulation of the galactose pathway genes in Saccharomyces cerevisiae. Distinct messenger RNAs specified by the Gali and Gal7 genes in the Gal7-Gal10-Gal1 cluster.
- Gene regulation at the right operator (OR) of bacteriophage lambda. II. OR1, OR2, and OR3: their roles in mediating the effects of repressor and cro.
- Lac repressor-operator interaction. I. Equilibrium studies.
- Multiple binding sites for polyomavirus large T antigen within regulatory sequences of polyomavirus DNA
- The organization and transcription of the galactose gene cluster of Saccharomyces.
- Homology among DNA-binding proteins suggests use of a conserved super-secondary structure
- A synthetic HIS4 regulatory element confers general amino acid control on the cytochrome c gene (CYC1) of yeast.
- A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene
- Transformation of intact yeast cells treated with alkali cations.
- Yeast transformation: a model system for the study of recombination.
- Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization.
- Regulation of the galactose pathway in Saccharomyces cerevisiae: induction of uridyl transferase mRNA and dependency on GAL4 gene function.
- Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product
- A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.
- Specific protein binding to far upstream activating sequences in polymerase II promoters.
- Specific DNA binding of GAL4, a positive regulatory protein of yeast.
- Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli.
- Binding of a simian virus 40 T antigen-related protein to DNA.
- Negatively supercoiled simian virus 40 DNA contains Z-DNA segments within transcriptional enhancer sequences
Cited by
- Distinct classes of transcriptional activating domains function by different mechanisms.
- CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. II. Missense mutation suggests alternative Zn fingers as discriminating agents of gene control.
- Functional domains of adenovirus type 5 E1a proteins.
- Epstein-Barr virus nuclear antigen forms a complex that binds with high concentration dependence to a single DNA-binding site
- A new class of yeast transcriptional activators.
- DNA affinity labeling of adenovirus type 2 upstream promoter sequence-binding factors identifies two distinct proteins
- The glutamine-rich activation domains of human Sp1 do not stimulate transcription in Saccharomyces cerevisiae
- Two "what if" experiments.
- Study of the Escherichia coli vsr endonuclease and its interaction with MutL
- Structure and regulation of the multigene family controlling maltose fermentation in budding yeast.
- Analysis of meiotic recombination initiation in Saccharomyces cerevisiae
- Transcription Factor Effector Domains
- HOW TO HUNT FOR INTERACTION PARTNERS OF MEMBRANE PROTEINS IN VIVO
- Smad interactors in bone morphogenetic protein signaling.
- A Field-Proven Yeast Two-Hybrid Protocol Used to Identify Coronavirus–Host Protein–Protein Interactions
- Protein-protein interactions involved in baculovirus DNA replication
- Structural and biochemical analysis of the death domain complex formed at the Fas receptor
- Identificação de proteínas ligantes de CRABP2, proteína envolvida na via de sinalização celular por ácido retinóico
- The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation
- Libraries for two-hybrid screening of yeast and hyphal growth forms in Zymoseptoria tritici
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