Homology among DNA-binding proteins suggests use of a conserved super-secondary structure
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Summary
Model-building studies indicate that this structure is important in DNA binding, and it is suggested that it may be a common feature of many DNA-binding proteins.
- Type
- article
- Published
- 1982-07-29
- Cited by
- 366
- References
- 45
- OpenAlex
- https://openalex.org/W1966327456
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4314897
Keywords
Repressor, Homology (biology), DNA, DNA-binding protein, Protein secondary structure
References
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- Principles of Protein Structure
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- Structural similarity in the DNA-binding domains of catabolite gene activator and cro repressor proteins.
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- Nucleotide sequence of the cro-cII-oop region of bacteriophage 434 DNA.
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- Regulation of SOS functions: purification of E. coli LexA protein and determination of its specific site cleaved by the RecA protein.
- DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli.
- The lambda repressor contains two domains.
- Similar amino acid sequences: chance or common ancestry?
- An amino-terminal fragment of lac repressor binds specifically to lac operator.
- Altered sequences changing the operator-binding properties of the Lac repressor: colinearity of the repressor protein with the i-gene map.
- Regulatory functions of the λ repressor reside in the amino-terminal domain
- Primary structure of the phage P22 repressor and its gene c2.
- Modification of tyrosine residues of the lactose repressor protein.
- A mutant of Escherichia coli showing constitutive expression of the lysogenic induction and error-prone DNA repair pathways.
- Mechanism of action of the cro protein of bacteriophage lambda.
Cited by
- Structure of the DNA-Eco RI endonuclease recognition complex at 3 A resolution.
- Stoichiometry of lac repressor binding to nonspecific DNA: three different complexes form.
- Molecular Evolution of Helix–Turn–Helix Proteins
- Chapter 1: Variation in form and function the helix-turn-helix regulators of the GntR superfamily.
- Combinatorial associations of regulatory proteins and the control of cell type in yeast.
- Gene Inhibition Using Genetic Suppressor Elements in Escherichia Coli JM109DE3 Cells
- Genetic analyses of cellular functions required for UV mutagenesis in Escherichia coli.
- Crystallizing catabolite gene activator protein with cAMP for structural analysis.
- A molecular code dictates sequence‐specific DNA recognition by homeodomains.
- Structural Studies of Flexible Biomolecules and a DNA-binding Protein
- Lambda repressor: a model system for understanding protein-DNA interactions and protein stability.
- Cell division inhibition gene dicB is regulated by a locus similar to lamboid bacteriophage immunity loci
- Nucleotide sequence analysis and comparison of the lexA genes from Salmonella typhimurium, Erwinia carotovora, Pseudomonas aeruginosa and Pseudomonas putida
- Nearest-neighbor effects in the structure and function of nucleic acids.
- Retroevolution of the structure of lambda Cro
- Estudios moleculares del sistema regulador de la degradación anaeróbica de benzoato en Azoarcus sp. CIB
- Genetic analyses of the roles of umuDC and mucAB in mutagenesis.
- Determining the functions of transcriptional regulatory genes of the npd gene cluster encoding 2,4,6-trinitrophenol degradation in Rhodococcus opacus HL PM-1
- Electrostatic deformation of DNA by a DNA-binding protein.
- New perch for the winged helix
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