The expanding universe of T-cell subsets: Th1, Th2 and more.
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Summary
The increasing number of T-cell subsets defined by cytokine patterns; the differentiation pathways of CD4+ and CD8+ T cells; the contribution of other cell types to these patterns; and the cytokine interactions during infection and pregnancy are discussed.
- Type
- review
- Published
- 1996-03-01
- Cited by
- 4,045
- References
- 86
- OpenAlex
- https://openalex.org/W1972922050
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28795991
Keywords
CD8, T cell, Immunology, Cytokine, Biology
References
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- Biology of Natural Killer Cells
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- Role of IL-4 and IFN-gamma in modulation of immunity to Borrelia burgdorferi in mice.
- Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo
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- Cytokine pattern in relation to disease progression in human immunodeficiency virus-infected children.
- A possible role of pre‐existing IgM/IgG antibodies in determining immune response type
- Evidence that calcineurin is rate-limiting for primary human lymphocyte activation.
- Specific immune response to staphylococcal antigens during long-lasting biomaterial implantation.
- Adhesion molecules in atopic dermatitis: patch tests elicited by house dust mite
- Progression of visceral leishmaniasis due to Leishmania infantum in BALB/c mice is markedly slowed by prior infection with Trichinella spiralis
- Immunopharmacology of oral betalactams.
- ELI-spot of Th-1 cytokine secreting PBMC's in multiple sclerosis: correlation with MRI lesions.
- The Salmonella typhimurium AhpC Polypeptide Is Not Essential for Virulence in BALB/c Mice but Is Recognized as an Antigen during Infection
- Immunoregulation of cytokines in infectious diseases (leprosy), future strategies.
- Sweet's syndrome: is the pathogenesis mediated by helper T cell type 1 cytokines?
- Determinant in Human Immunodeficiency Virus Type 1 for Efficient Replication under Cytokine-Induced CD4+ T-Helper 1 (Th1)- and Th2-Type Conditions
- Evidence for suppressed activity of the transcription factor NFAT1 at its proximal binding element P0 in the IL-4 promoter associated with enhanced IL-4 gene transcription in T cells of atopic patients.
- Hypothesis: is renal allograft rejection initiated by the response to injury sustained during the transplant process?
- Trichuris muris: host intestinal epithelial cell hyperproliferation during chronic infection is regulated by interferon-gamma.
- Cytokine gene polymorphisms predict acute graft rejection following renal transplantation.
- An activation-responsive element in single C motif-1/lymphotactin promoter is a site of constitutive and inducible DNA-protein interactions involving nuclear factor of activated T cell.
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