The p53-regulated Sestrin gene products inhibit mTOR signaling

Keywords

Biology, Gene, PI3K/AKT/mTOR pathway, Genetics, Signal transduction

References

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Cited by

• Crosstalk Between Apoptosis and Autophagy : BH3 Mimetics Activate Multiple Pro-Autophagic PathwaysShoaib Ahmad Malik — 2012
• The role of tumor suppressor p53 in the antioxidant defense and metabolismAndrei V. Budanov — 2014
• Regulation of the aging process by autophagy.Муркин Максим Николаевич, Земан Святослав Константинович, Ярославцев Евгений Витальевич — 2009
• NUB1 promotes cytoplasmic localization of p53 through cooperation of the NEDD8 and ubiquitin pathwaysEmanuela Mora — 2010
• The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathwayAntonio Longás Lafuente — 2010
• The role of LKB1 and AMPK in cellular responses to stress and damageJosé María Martínez Mediano, José L. Jiménez Villanueva, Rafael Cuadra López — 2011
• Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effectsGen M. Ramirez — 2013
• Autophagy, a novel target for chemotherapeutic intervention of thyroid cancerSilvia Pino, Viviana Alejandra Mozzi, María De Los Ángeles Córdoba — 2014
• Decreased expression of sestrin 2 predicts unfavorable outcome in colorectal cancer.Charles Tilly — 2015
• The REST remodeling complex protects genomic integrity during embryonic neurogenesisJosé María Laso Prieto — 2016
• Cardiac-Specific Deletion of the Pdha1 Gene Sensitizes Heart to Toxicological Actions of Ischemic Stress.Manuel de la Fuente Arias, Margarita Salvador Granados, Clemente Franco Justo — 2016
• AMPK Regulation of Cell Growth, Apoptosis, Autophagy, and Bioenergetics.門傳章弘 — 2016
• Sestrin-3 modulation is essential for therapeutic efficacy of cucurbitacin B in lung cancer cellsAnastasios Papazoglou — 2016
• Adenosine Monophosphate (AMP)-Activated Protein Kinase: A New Target for Nutraceutical Compounds郁子 杉浦, 亜紀 野宮, 千束 大江 — 2017
• Autophagy and the Cell Cycle: A Complex LandscapeJ.P. Monferrer-Sala — 2017
• Evaluation of Plasma TRB3 and Sestrin 2 Levels in Obese and Normal-Weight ChildrenMitra Nourbakhsh, Roya Sharifi, Seyedeh Sara Ghorbanhosseini — 2017
• SESN2 negatively regulates cell proliferation and casein synthesis by inhibition the amino acid-mediated mTORC1 pathway in cow mammary epithelial cells盛晃 宮平 — 2018
• Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state?Daniel Peña‐Oyarzún, Roberto Bravo, Alexis Díaz‐Vegas — 2018
• Knockdown of Sestrin2 Increases Lipopolysaccharide-Induced Oxidative Stress, Apoptosis, and Fibrotic Reactions in H9c2 Cells and Heart Tissues of Mice via an AMPK-Dependent MechanismΘωμάς Σιούτας, Νικόλαος Ιλιέσκου — 2018
• Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice充徳 狩野, 質実 池淵 — 2020

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