The role of the Angiopoietins in vascular morphogenesis
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Summary
The better mechanistic understanding of the Ang/Tie system is gradually paving the way toward the rationale exploitation of this vascular signaling system as a therapeutic target for neoplastic and non-neoplastic diseases.
- Type
- review
- Published
- 2009-05-16
- Cited by
- 416
- References
- 162
- OpenAlex
- https://openalex.org/W1970016838
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10906390
Keywords
Angiopoietin receptor, Angiopoietin, Angiogenesis, Mural cell, Autocrine signalling
References
- Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt
- Angiopoietin-1 and Angiopoietin-2 Share the Same Binding Domains in the Tie-2 Receptor Involving the First Ig-like Loop and the Epidermal Growth Factor-like Repeats*
- Potential role of the angiopoietin/tie2 system in ischemia-induced retinal neovascularization.
- tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors.
- Mast cell-derived angiopoietin-1 plays a critical role in the growth of plasma cell tumors.
- Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis.
- The thin prep rat aortic ring assay: A modified method for the characterization of angiogenesis in whole mounts
- Role of serum angiopoietin‐2 level in screening for esophageal squamous cell cancer and its precursors
- Differential expression of angiopoietin‐1 and angiopoietin‐2 in colon carcinoma
- Angiopoietin‐3, a novel member of the angiopoietin family
- Tie receptors: new modulators of angiogenic and lymphangiogenic responses
- Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors.
- Expression and function of angiopoietin-1 in breast cancer
- Angiopoietin‐1‐induced phosphatidyl‐inositol 3‐kinase activation prevents neuronal apoptosis
- Identification of a soluble form of the angiopoietin receptor TIE-2 released from endothelial cells and present in human blood
- Identification of a family of alternatively spliced mRNA species of angiopoietin-1.
- Angiopoietin‐1 negatively regulates expression and activity of tissue factor in endothelial cells
- Angiopoietins, growth factors, and vascular morphology in early arthritis.
- Expression of tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage.
- Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development.
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- Molecular Biology of Human Herpesvirus 8: Novel Functions and Virus–Host Interactions Implicated in Viral Pathogenesis and Replication
- Ilościowa ocena krążących komórek śródbłonka, krążących komórek progenitorowych i czynnika von Willebranda u kobiet w ciąży powikłanej nadciśnieniem tętniczym
- Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF‐A and TGFβ2 in vascular abnormalization
- Angiopoietins in angiogenesis.
- Aggressive primary cutaneous B‐cell lymphomas show increased Angiopoietin‐2‐induced angiogenesis
- Characterization of microparticles in patients with venous malformations of the head and neck.
- In Vitro Development of Engineered Lung Tissue
- Opportunities and challenges in tumor angiogenesis research: back and forth between bench and bed.
- A study of the role of monocyte functional subpopulations in patients with carotid atherosclerosis and coronary artery disease
- Targeting angiogenesis in cancer therapy.
- VE-cadherin in vascular development: a coordinator of cell signaling and tissue morphogenesis.
- Biomolecule Functionalization of Diamond Surfaces for Implant Applications - A Theoretical Study
- Abl Family Kinases Regulate Endothelial Function
- Comparaison de la capacité de différenciation en cellules endothéliales, de deux types de cellules souches mésenchymateuses issues de la gelée de Wharton et de la moelle osseuse
- 血管生成素1在G-CSF诱导的造血干／祖细胞动员中的表达变化
- Developing Somatic Hypermutation as a Protein Engineering Tool to Study Angiopoietin Binding
- Isolation and characterization of human endothelial colony forming cells (ECFCs) and effect of oxidative stress on their differentiation
- Venous thromboembolism in patients with cancer undertaking chemotherapy
- [Role of circulating angiogenic factors in diabetic kidney disease].
- Significant decrease in maternal serum concentrations of angiopoietin‐1 and ‐2 after delivery
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