Targeting angiogenesis in cancer therapy.
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Summary
This review focuses on signaling pathways related with tumor angiogenesis and several antiangiogenic agents approved by the United States Food and Drug Administration or under investigation.
- Type
- review
- Published
- 2011-12-01
- Cited by
- 50
- References
- 84
- Access
- Open access
- OpenAlex
- https://openalex.org/W132539193
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2761874
Keywords
Angiogenesis, Cancer therapy, Cancer, Medicine, Antiangiogenic therapy
References
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- Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation.
- Vascular-specific growth factors and blood vessel formation
- Characterization of a novel member of the FGF family, XFGF-20, in Xenopus laevis.
- Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos.
- Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
- The role of the Angiopoietins in vascular morphogenesis
- Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.
- The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth
- Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors.
- Tumor angiogenesis: therapeutic implications.
- VEGF-Trap: A VEGF blocker with potent antitumor effects
- Molecular regulation of angiogenesis and lymphangiogenesis
- The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions.
- The biology of vascular endothelial growth factor.
Cited by
- Novel Synergistic Therapy for Metastatic Breast Cancer: Magnetic Nanoparticle Hyperthermia of the Neovasculature Enhanced by a Vascular Disruption Agent
- Extraction, Isolation, Structural Characterization and Anti-Tumor Properties of an Apigalacturonan-Rich Polysaccharide from the Sea Grass Zostera caespitosa Miki
- Effets antiangiogéniques du régime méditerranéen : inhibition de l'action du VEGF par les composés phytochimiques de l'huile d'olive
- A novel in vivo tumor oxygen profiling assay: Combining functional and molecular imaging with multivariate mathematical modeling
- The pan-deacetylase inhibitor panobinostat affects angiogenesis in hepatocellular carcinoma models via modulation of CTGF expression.
- Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature
- Anti-angiogenic therapies for metastatic colorectal cancer: current and future perspectives.
- Tumor microvessel density–associated mast cells in canine nodal lymphoma
- Autophagy triggered by magnolol derivative negatively regulates angiogenesis
- Oroxylin A, a classical natural product, shows a novel inhibitory effect on angiogenesis induced by lipopolysaccharide
- Role of bevacizumab in colorectal cancer growth and its adverse effects: a review.
- Anti-metastatic and anti-angiogenic activities of sulfated polysaccharide of Sepiella maindroni ink.
- Preparation, antiangiogenic and antitumoral activities of the chemically sulfated glucan from Phellinus ribis.
- Potent anti-angiogenesis and anti-tumor activity of a novel human anti-VEGF antibody, MIL60
- TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research
- Macrophage migration inhibitory factor: a potential marker for cancer diagnosis and therapy.
- Interrogating Tumor Metabolism and Tumor Microenvironments Using Molecular Positron Emission Tomography Imaging. Theranostic Approaches to Improve Therapeutics
- Angiogenic factors as potential drug target: efficacy and limitations of anti-angiogenic therapy.
- A morphometric tool applied to angiogenesis research based on vessel segmentation
- Synergistic Cytotoxic Effect of Gold Nanoparticles and 5-Aminolevulinic Acid-Mediated Photodynamic Therapy against Skin Cancer Cells
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