Structure, mechanism, and regulation of soluble adenylyl cyclases - similarities and differences to transmembrane adenylyl cyclases.

Keywords

Mechanism (biology), Adenylyl cyclase, Transmembrane protein, Chemistry, Cell biology

References

• Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect.Gloria Esposito, Byjay S. Jaiswal, Fang Xie — 2004
• Capturing adenylyl cyclases as potential drug targetsFrancisco León Crespo — 2009
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• Crystal structure of the Alpha subunit PAS domain from soluble guanylyl cyclaseRahul Purohit, A. Weichsel, W.R. Montfort — 2013
• Adenylyl cyclase Rv0386 from Mycobacterium tuberculosis H37Rv uses a novel mode for substrate selectionLucila I. Castro, Corinna Hermsen, Joachim E. Schultz — 2005
• Stereochemistry of the mammalian adenylate cyclase reaction.F. Eckstein, Paul J. Romaniuk, Warren Heideman — 1981
• Structure, signaling mechanism and regulation of natriuretic peptide receptor-guanylate cyclaseKunio S. Misono, John S. Philo, Tsutomu Arakawa — 2011
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• Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.Yanqiu Chen, Martin J. Cann, Tatiana N. Litvin — 2000
• Emerging mitochondrial signaling mechanisms in physiology, aging processes, and as drug targets.Mahadevan Lakshminarasimhan, Clemens Steegborn — 2011
• Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals.Jochen Buck, Meeghan L. Sinclair, Lissy Schapal — 1999
• Kinetic Properties of “Soluble” Adenylyl CyclaseTatiana N. Litvin, Margarita Kamenetsky, Alla S. Zarifyan — 2003
• Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.J.J.G. Tesmer, Roger K. Sunahara, Alfred G. Gilman — 1997
• Adenylyl cyclases as innovative therapeutic goals.Barbara Pavan, Carla Biondi, Alessandro Dalpiaz — 2009
• Molecular basis for P-site inhibition of adenylyl cyclase.J.J.G. Tesmer, Carmen Dessauer, Roger K. Sunahara — 2000
• Activation of PDE10 and PDE11 Phosphodiesterases*Ronald Jäger, Corina Russwurm, Frank Schwede — 2011
• Specific expression of soluble adenylyl cyclase in male germ cellsMeeghan L. Sinclair, Xiangyuan Wang, Melissa Mattia — 2000
• Soluble Adenylyl Cyclase Antibody Profile as a Diagnostic Adjunct in the Assessment of Pigmented LesionsCynthia M. Magro — 2011

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• Phosphodiesterase 4D: an enzyme to rememberDavid Puyet — 2015
• Targeting protein–protein interactions in complexes organized by A kinase anchoring proteinsAna I. Calejo, Kjetil Taskén — 2015
• Coupling of β1-adrenergic receptor to type 5 adenylyl cyclase and its physiological relevance in cardiac myocytes.Takashi Tsunematsu, Satoshi Okumura, Yasumasa Mototani — 2015
• A Universal Stress Protein (USP) in Mycobacteria Binds cAMPArka Banerjee, Ramona S. Adolph, Jayashree Gopalakrishnapai — 2015
• cCMP and cUMP: emerging second messengers.Roland Seifert — 2015
• From canonical to non-canonical cyclic nucleotides as second messengers: pharmacological implications.Roland Seifert, Erich Schneider, Heike Bähre — 2015
• Major regulatory mechanisms involved in sperm motilityMário Sousa, Rute Pereira, Rosália Sá — 2015
• Neuroendocrine Differentiation and Epithelial to Mesenchymal Transition in Prostate Cancer: cAMP-Dependent Signaling as a Therapeutic TargetCharles E. Myers — 2015
• Geranylgeraniol enhances testosterone production via the cAMP/protein kinase A pathway in testis-derived I-10 tumor cellsHsin‐Jung Ho, Hitoshi Shirakawa, Risa Yoshida — 2016
• Biophotography: concepts, applications and perspectivesChristian CR Renicke, Christof Taxis — 2016
• Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site*S. Kleinboelting, Lavoisier Ramos‐Espiritu, Hannes Buck — 2016
• Soluble Adenylyl Cyclase Regulates Bile Salt‐Induced Apoptosis in Human CholangiocytesJung‐Chin Chang, Simei Go, Dirk R. de Waart — 2016
• A novel biosensor to study cAMP dynamics in cilia and flagellaShatanik Mukherjee, Vera Jansen, Jan F. Jikeli — 2016
• De Novo Mutations in PDE10A Cause Childhood-Onset Chorea with Bilateral Striatal LesionsNiccolò E. Mencacci, Erik-Jan Kamsteeg, Kosuke Nakashima — 2016
• Cyclic Nucleotides as Mediators of Acinar and Ductal FunctionMaría E. Sabbatini — 2016
• Neuroprotective effects of PGC-1α activators in dopaminergic neuronsJohanna Mäkelä — 2016
• New Developments in Platelet Cyclic Nucleotide Signalling: Therapeutic ImplicationsNathan Procter, Nicola Hurst, Vivek B. Nooney — 2016
• C-di-GMP Synthesis: Structural Aspects of Evolution, Catalysis and Regulation.Tilman Schirmer — 2016
• Development of a method for the investigation of protein carbamylation by CO2J. Janus — 2016
• Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclaseLavoisier Ramos‐Espiritu, S. Kleinboelting, Felipe Navarrete — 2016

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