Capturing adenylyl cyclases as potential drug targets

Keywords

Political science

References

• Inhibition of adenylate cyclase by adenosine analogues in preparations of broken and intact human platelets. Evidence for the unidirectional control of platelet function by cyclic AMP.Markus Pelz, Markus Talg, Christoph Lackhove — 1978
• Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: An in situ hybridization studyLynn V. Dicks — 1994
• Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice.Mauricio Montiel Figueiras — 2000
• Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect.Gloria Esposito, Byjay S. Jaiswal, Fang Xie — 2004
• Narrative Review: Pharmacotherapy for Chronic Heart Failure: Evidence from Recent Clinical TrialsFlora Louisa Lugard — 2005
• Cardiac adrenoceptors: physiological and pathophysiological relevance.Otto‐Erich Brodde, Heike Bruck, Kirsten Leineweber — 2006
• Signaling pathways in sensitization: toward a nociceptor cell biology.Manu Gupta, K S Preeti, Vijit Singh — 2007
• Daily spermatozoal production and epididymal spermatozoal reserves of the human male.R. P. Amann, Stuart S. Howards — 1980
• Structures, mechanism, regulation and evolution of class III nucleotidyl cyclases.S. C. Sinha, Stephen R. Sprang — 2006
• Therapeutic benefit of PDE4 inhibitors in inflammatory diseases.Sunanda G. Dastidar, Deepa Rajagopal, Abhijit Ray — 2007
• Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addictionMacDonald J. Christie — 2008
• Protein associated with Myc (PAM) is involved in spinal nociceptive processingCorina Ehnert, Irmgard Tegeder, Sandra Pierre — 2004
• Type-specific Regulation of Adenylyl CyclaseTakeshi Onda, Yoko Hashimoto, Masashi Nagai — 2001
• Functional analyses of type V adenylyl cyclase.Tarun B. Patel, Claus Wittpoth, Ann Barbier — 2002
• Mechanism of Galpha i-mediated inhibition of type V adenylyl cyclase.Carmen Dessauer, Misty Chen‐Goodspeed, Jun Chen — 2002
• Capacitation of mouse spermatozoa. II. Protein tyrosine phosphorylation and capacitation are regulated by a cAMP-dependent pathway.Pablo E. Visconti, Grace D. Moore, Janice L. Bailey — 1995
• Impaired D2 Dopamine Receptor Function in Mice Lacking Type 5 Adenylyl CyclaseKo-Woon Lee, Jang Hee Hong, In Young Choi — 2002
• Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.Yanqiu Chen, Martin J. Cann, Tatiana N. Litvin — 2000
• Differential Inhibition of Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by Purine and Pyrimidine Nucleotides*Andreas Gille, Gerald H. Lushington, Tung‐Chung Mou — 2004
• Downregulation of adenylylcyclase types V and VI mRNA levels in pacing-induced heart failure in dogs.Yuki Ishikawa, Steve Sorota, K Kiuchi — 1994

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