Transient Regenerative Potential of the Neonatal Mouse Heart
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Summary
It is found that the hearts of 1-day-old neonatal mice can regenerate after partial surgical resection, but this capacity is lost by 7 days of age, which means that for a brief period after birth, the mammalian heart appears to have the capacity to regenerate.
- Type
- article
- Published
- 2011-02-25
- Cited by
- 2,487
- References
- 17
- Access
- Open access
- OpenAlex
- https://openalex.org/W1969038150
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:206531264
Keywords
Transient (computer programming), Mammalian heart, Regeneration (biology), Biology, Cell biology
References
- A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.
- Chimerism of the transplanted heart.
- Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
- Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development.
- Response of the adult newt ventricle to injury.
- Compensatory growth of healthy cardiac cells in the presence of diseased cells restores tissue homeostasis during heart development.
- Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury.
- Evidence for cardiomyocyte renewal in humans
- Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
- Cardiomyocyte cell cycle control and growth estimation in vivo--an analysis based on cardiomyocyte nuclei.
- Heart Regeneration in Zebrafish
- Sequential myofibrillar breakdown accompanies mitotic division of mammalian cardiomyocytes
- Cardiac myocyte cell cycle control in development, disease, and regeneration.
- Getting to the heart of regeneration in zebrafish.
- Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes
- Targeted Expression of Cyclin D2 Results in Cardiomyocyte DNA Synthesis and Infarct Regression in Transgenic Mice
Cited by
- Engineering contractile myocardial tissue using extracellular matrix scaffolds
- The cardiomyocyte cell cycle in hypertrophy, tissue homeostasis, and regeneration.
- Role of stem cells in cardiovascular biology
- MicroRNA-processing Enzyme Dicer Is Required in Epicardium for Coronary Vasculature Development*
- Cardiac Regeneration from Activated Epicardium
- Poor engraftment potential of epicardial progenitors upon intramyocardial transplantation into the neonatal mouse heart.
- Patching the Heart: Cardiac Repair from Within and Outside
- Harnessing the power of dividing cardiomyocytes
- DOT1L-mediated H3K79me2 modification critically regulates gene expression during cardiomyocyte differentiation
- Cardiac Regeneration in Children
- Generation of new cardiomyocytes after injury: de novo formation from resident progenitors vs. replication of pre-existing cardiomyocytes.
- Defining the Limit of Embryonic Heart Regeneration.
- Cardiac Regeneration
- An early post‐traumatic reaction of lymph‐heart striated muscle fibers in adult frog Rana temporaria during the first postoperative week: An electron microscopic and autoradiographic study
- Abcg2-Labeled Cells Contribute to Different Cell Populations in the Embryonic and Adult Heart
- Possible Muscle Repair in the Human Cardiovascular System
- Cardiac Thyroid Hormone Metabolism and Heart Failure
- Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration
- Non-coding microRNAs for cardiac regeneration: Exploring novel alternatives to induce heart healing
- Protein O-GlcNAcylation in Cardiac Pathologies: Past, Present, Future
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- Heart Regeneration in Adult Mammals after Myocardial Damage.
- Advances in understanding the mechanism of zebrafish heart regeneration.