Evidence for cardiomyocyte renewal in humans
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Summary
The capacity to generate cardiomyocytes in the adult human heart suggests that it may be rational to work toward the development of therapeutic strategies aimed at stimulating this process in cardiac pathologies.
- Type
- article
- Published
- 2008-10-14
- Cited by
- 3,114
- References
- 28
- Access
- Open access
- OpenAlex
- https://openalex.org/W2101986300
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21986547
Keywords
Myocyte, Life span, Human heart, Cell biology, Biology
References
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- Replacement Rates for Human Tissue from Atmospheric Radiocarbon
- Evidence that human cardiac myocytes divide after myocardial infarction.
- Retrospective birth dating of cells in humans.
- Myocyte renewal and ventricular remodelling
- Forensics: Age written in teeth by nuclear tests
- 14C dating with the bomb peak: An application to forensic medicine
- Lives of a heart cell: tracing the origins of cardiac progenitors.
- Further Investigations of the Transfer of Bomb 14C to Man
- DNA repair in terminally differentiated cells.
- Regenerating the heart
- Distribution of Radiocarbon from Nuclear Tests
- Biology of the troponin complex in cardiac myocytes.
- Origins and fates of cardiovascular progenitor cells.
- Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
Cited by
- Factors involved in signal transduction during vertebrate myogenesis.
- CD133-Positive Cells for Cardiac Stem Cell Therapy: Current Status and Outlook.
- Pathobiology of troponin elevations: do elevations occur with myocardial ischemia as well as necrosis?
- The cardiomyocyte cell cycle in hypertrophy, tissue homeostasis, and regeneration.
- Mechanisms of exercise‐induced improvements in the contractile apparatus of the mammalian myocardium
- Control of autocrine and paracrine myocardial signals: an emerging therapeutic strategy in heart failure
- Age-Dependent Denaturation of Enzymes in the Human Lens: A Paradigm for Organismic Aging?
- Stem cell therapy in cardiovascular disorders.
- Role of stem cells in cardiovascular biology
- Update on cardiac stem cell therapy in heart failure
- Human Placenta-Derived Multipotent Cells (hPDMCs) Modulate Cardiac Injury: From Bench to Small and Large Animal Myocardial Ischemia Studies
- Cardiac Side Population Cells: Moving toward the Center Stage in Cardiac Regeneration
- Regeneration in heart disease – Is ECM the key?
- Cellular therapy promotes endogenous stem cell repair
- Cardiac Regeneration from Activated Epicardium
- Mechanisms and consequences of injury and repair in older organ transplants
- Harnessing the power of dividing cardiomyocytes
- Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers
- Cardiac Regeneration in Children
- Sublethal Caspase Activation Promotes Generation of Cardiomyocytes from Embryonic Stem Cells
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