Caloric restriction delays disease onset and mortality in rhesus monkeys
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Summary
Findings of a 20-year longitudinal adult-onset CR study in rhesus monkeys aimed at filling this critical gap in aging research demonstrate that CR slows aging in a primate species.
- Type
- article
- Published
- 2009-07-10
- Cited by
- 2,292
- References
- 22
- Access
- Open access
- OpenAlex
- https://openalex.org/W1966132436
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:75432888
Keywords
Caloric theory, Calorie, Physiology, Disease, Calorie restriction
References
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- An epidemic of complex dysmorphologic syndromes in southeast Spain?
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- The aging brain.
- Mortality and morbidity in laboratory-maintained Rhesus monkeys and effects of long-term dietary restriction.
- Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study.
- A voxel-based morphometric study of ageing in 465 normal adult human brains
- Attenuation of sarcopenia by dietary restriction in rhesus monkeys.
- Aging and survival: the genetics of life span extension by dietary restriction.
- Caloric restriction in humans.
- Aging, health risks, and cumulative disability.
Cited by
- Forty Percent Methionine Restriction Decreases Mitochondrial Oxygen Radical Production and Leak at Complex I During Forward Electron Flow and Lowers Oxidative Damage to Proteins and Mitochondrial DNA in Rat Kidney and Brain Mitochondria
- Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
- Sirtuins and Their Relevance to the Kidney
- Systematic Identification of TOR Downstream Effectors Using Random-Walks on the Yeast Interactome
- Glucose Reduction Prevents Replicative Senescence and Increases Mitochondrial Respiration in Human Mesenchymal Stem Cells
- The caloric restriction paradigm: implications for healthy human aging
- Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects
- Department of Veterans Affairs Geriatric Research, Education and Clinical Centers: Translating Aging Research into Clinical Geriatrics
- The Antiaging Approach for the Treatment of Dry Eye
- Cognitive dysfunction with aging and the role of inflammation
- The role of extracellular form of visfatin (eNAMPT) in modulating stress responses in cultured myocytes as a model of skeletal muscle ageing
- Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance
- Utilizing calorie restriction to evaluate the role of sirtuins in healthspan and lifespan of mice.
- Impact of natural products in modern drug development.
- Autophagy in axonal degeneration in glaucomatous optic neuropathy.
- Calorie restriction does not restore brain mitochondrial function in P301L tau mice, but it does decrease mitochondrial F0F1-ATPase activity.
- Dietary Restriction Affects Neuronal Response Property and GABA Synthesis in the Primary Visual Cortex
- Balanced intake of protein and carbohydrate maximizes lifetime reproductive success in the mealworm beetle, Tenebrio molitor (Coleoptera: Tenebrionidae).
- Pre-adult famine exposure and subsequent colorectal cancer risk in women.
- Caloric Restriction Research: New Perspectives on the Biology of Aging.
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