Utilizing calorie restriction to evaluate the role of sirtuins in healthspan and lifespan of mice.
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Summary
The methods outlined in this chapter are intended to provide a guide to help the aging community to use and interpret experimental calorie restriction properly and the importance of healthspan and the use of repeated measures to assess metabolic health during lifespan experiments are strongly emphasized.
- Type
- article
- Published
- 2013-01-01
- Cited by
- 9
- References
- 28
- OpenAlex
- https://openalex.org/W24014415
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44623074
Keywords
Humanities, Philosophy, Psychology
References
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- Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice.
- SIRTUIN 1 AND SIRTUIN 3: PHYSIOLOGICAL MODULATORS OF METABOLISM
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- SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice
- Impact of caloric restriction on health and survival in rhesus monkeys: the NIA study
- Caloric restriction lowers blood pressure in the spontaneously hypertensive rat.
- Sirtuin activators mimic caloric restriction and delay ageing in metazoans
- A guide to analysis of mouse energy metabolism
- Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase
- Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer syndrome
- SRT1720 improves survival and healthspan of obese mice
Cited by
- Mouse models and aging: longevity and progeria.
- A new facet of ADP-ribosylation reactions: SIRTs and PARPs interplay.
- Can restricting calories help you to live longer?
- Putting the balance back in diet.
- Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index.
- Positive effects of prolonged caloric restriction on the population of very small embryonic-like stem cells – hematopoietic and ovarian implications
- P66Shc-SIRT1 Regulation of Oxidative Stress Protects Against Cardio-cerebral Vascular Disease
- Developmental aspects of senescence
- Contemporary approaches in anti-aging therapy
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