Tumor antigen-specific CD4+ T cells in cancer immunity: from antigen identification to tumor prognosis and development of therapeutic strategies.

Keywords

Antigen, Priming (agriculture), Immunology, Tumor antigen, Biology

References

• Disease-associated Bias in T Helper Type 1 (Th1)/Th2 CD4+ T Cell Responses Against MAGE-6 in HLA-DRB10401+ Patients With Renal Cell Carcinoma or MelanomaMalcolm K. Jones, R. Marno, Hannah M. Buchanan‐Smith — 2002
• HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trialN. Persat — 2013
• Identification of helper T-cell epitopes that encompass or lie proximal to cytotoxic T-cell epitopes in the gp100 melanoma tumor antigen.Hiroya Kobayashi, Jun Lü, Esteban Celis — 2001
• Spontaneous CD4+ T Cell Responses against TRAG-3 in Patients with Melanoma and Breast Cancers1Bratislav Janjic, Pedro Andrade, Xiaofei Wang — 2006
• Recognition of a New ARTC1 Peptide Ligand Uniquely Expressed in Tumor Cells by Antigen-Specific CD4+ Regulatory T Cells1Helen Y. Wang, Guangyong Peng, Zhong Guo — 2005
• CD4+ T cells against human papillomavirus‐18 E7 in patients with high‐grade cervical lesions associate with the absence of the virus in the cervixSamantha Seresini, Massimo Origoni, Luigi Caputo — 2010
• IFN-γ Produced by Human Papilloma Virus-18 E6-Specific CD4+ T Cells Predicts the Clinical Outcome after Surgery in Patients with High-Grade Cervical Lesions1Samantha Seresini, Massimo Origoni, Flavia Lillo — 2007
• Identification of Novel Subdominant Epitopes on the Carcinoembryonic Antigen Recognized by CD4+ T Cells of Lung Cancer Patients1Mariacristina Crosti, Renato Longhi, Giuseppe Consogno — 2006
• Identification of an SSX-2 Epitope Presented by Dendritic Cells to Circulating Autologous CD4+ T Cells1Maha Ayyoub, Charles S. Hesdorffer, Geneviève Metthez — 2004
• CD4+ Th2 Cell Recognition of HLA-DR-Restricted Epitopes Derived from CAMEL: A Tumor Antigen Translated in an Alternative Open Reading FrameElisabeth H. Slager, Martina Borghi, Carolien E. van der Minne — 2003
• NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells.Hassane M. Zarour, Bernard Maillère, Vladimir Brusić — 2002
• Several common HLA-DR types share largely overlapping peptide binding repertoires.Scott Southwood, John Sidney, Akihiro Kondo — 1998
• Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen.Rong‐Fu Wang, Xiang Wang, Alicia C. Atwood — 1999
• Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.Gabriela Bindea, Bernhard Mlecnik, Marie Tosolini — 2013
• The Present and Future of Peptide Vaccines for Cancer: Single or Multiple, Long or Short, Alone or in Combination?Craig L. Slingluff — 2011
• Increased intratumoral IL-22-producing CD4+ T cells and Th22 cells correlate with gastric cancer progression and predict poor patient survivalYuan Zhuang, Liu‐sheng Peng, Yongliang Zhao — 2012
• Interleukin 22-producing CD4+ T cells in malignant pleural effusion.Zhijian Ye, Qiong Zhou, Wen Yin — 2012
• Targeting CD4(+) T-helper cells improves the induction of antitumor responses in dendritic cell-based vaccination.Erik H.J.G. Aarntzen, I. Jolanda M. de Vries, W. Joost Lesterhuis — 2013
• MHC class II restricted tumor antigens and the role of CD4+ T cells in cancer immunotherapy.Suzanne L. Topalian — 1994
• Vaccination with Recombinant NY-ESO-1 Protein Elicits Immunodominant HLA-DR52b-restricted CD4+ T Cell Responses with a Conserved T Cell Receptor RepertoireGilles Bioley, Christelle Dousset, Alice Yeh — 2009

Cited by

• A universal anti‐cancer vaccine: Chimeric invariant chain potentiates the inhibition of melanoma progression and the improvement of survivalMišo Mudrić — 2018
• Personalized approaches to active immunotherapy in cancer.Eran Ophir, Sara Bobisse, George Coukos — 2016
• Low expression of Bin1, along with high expression of IDO in tumor tissue and draining lymph nodes, are predictors of poor prognosis for esophageal squamous cell cancer patientsYunlong Jia, Hongyan Wang, Yu Wang — 2015
• Interest of Tumor-Specific CD4 T Helper 1 Cells for Therapeutic Anticancer VaccineJeanne Galaine, Christophe Borg, Yann Godet — 2015
• Combined Tumor Cell-Based Vaccination and Interleukin-12 Gene Therapy Polarizes the Tumor Microenvironment in MiceMagdalena Jarosz–Biej, Ryszard Smolarczyk, Tomasz Cichoń — 2015
• Peptide Vaccines for Treatment of Colon Cancer: Have We Made Progress?Walid L. Shaib, Daniel A. Goldstein, Bassel F. El‐Rayes — 2014
• HER2-Specific Vaccines for HER2-Positive Breast Cancer ImmunotherapyMaxwell Omabe, Shahid Ahmed, Amer Sami — 2015
• Quantum dot-based multiplexed imaging in malignant ascites: a new model for malignant ascites classificationYan Li, Weijuan Zeng, Chun‐Wei Peng — 2015
• Low‐dose metronomic chemotherapy with cisplatin enhanced immunity in a murine model of ectopic cervical cancerChing‐Chou Tsai, Jian‐Tai Qiu, Chih‐Wen Tseng — 2016
• Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survivalGiulia Di Lullo, Magda Marcatti, Silvia Heltai — 2015
• Non-redundant roles for Th17 and Th22 cells in multiple myeloma clinical correlatesGiulia Di Lullo, Magda Marcatti, Maria Pia Protti — 2016
• Antitumor Activity of the Chinese Medicine JC-001 Is Mediated by Immunomodulation in a Murine Model of Hepatocellular CarcinomaMeng-Hsien Chuang, Jinghua Tsai Chang, Li‐Jin Hsu — 2016
• Low Level of Blood CD4+ T Cells Is an Independent Predictor of Inferior Progression‐free Survival in Diffuse Large B‐cell LymphomaJulia Judd, Essel Dulaimi, Tianyu Li — 2017
• Immunotherapy of MelanomaCarolin Bender, Jessica C. Hassel, Alexander Enk — 2016
• Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexityRuth Dannenfelser, Marianne Nome, Andliena Tahiri — 2017
• T cell-intrinsic TLR2 stimulation promotes IL-10 expression and suppressive activity by CD45RbHi T cellsJanice Jun, Mark B. Jones, Douglas M. Oswald — 2017
• Aldehyde dehydrogenase in regulatory T‐cell development, immunity and cancerChristopher G. Bazewicz, Saketh S. Dinavahi, Todd D. Schell — 2018
• Composition and Clinical Impact of the Immunologic Tumor Microenvironment in Oral Squamous Cell CarcinomaMelanie Boxberg, Lena Leising, Katja Steiger — 2018
• Immunomodulatory Drugs in the Context of Autologous Hematopoietic Stem Cell Transplantation Associate With Reduced Pro-tumor T Cell Subsets in Multiple MyelomaGiulia Di Lullo, Magda Marcatti, Silvia Heltai — 2019
• Tumor progression mechanisms: Insights from the central immune regulation of tissue homeostasisNatalya Lisovska, Nasrulla Shanazarov — 2019

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