Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy
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Summary
Recommendations are made that focus on the complexity of the tumor microenvironment, with its diversity of immune genes, proteins, cells, and pathways naturally present at baseline and in circulation, and novel tools to aid in such broad analyses.
- Type
- article
- Published
- 2017-05-16
- Cited by
- 222
- References
- 185
- Access
- Open access
- OpenAlex
- https://openalex.org/W28515944
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28891548
Keywords
Humanities, Philosophy, Art
References
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- Baseline relative eosinophil count as a predictive biomarker for ipilimumab treatment in advanced melanoma
- Predicting response and toxicity to immune checkpoint inhibitors using routinely available blood and clinical markers
- Patent trend and competitive analysis of cancer immunotherapy in the United States
- Discovery and application of immune biomarkers for hematological malignancies
- The Society for Immunotherapy of Cancer Biomarkers Task Force Recommendations Review
- Migrating into the Tumor: a Roadmap for T Cells.
- PD-L1 Testing in Guiding Patient Selection for PD-1/PD-L1 Inhibitor Therapy in Lung Cancer
- Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment
- T cell densities in brain metastases are associated with patient survival times and diffusion tensor MRI changes
- A transatlantic perspective on the integration of immuno-oncology prognostic and predictive biomarkers in innovative clinical trial design.
- High-Dimensional Profiling of Tumor-Specific Immune Responses: Asking T Cells about What They “See” in Cancer
- A primer on recent developments in cancer immunotherapy, with a focus on neoantigen vaccines
- PD-L1 and Emerging Biomarkers in PD-1/PD-L1 Blockade Therapy
- Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib
- Antitumor in situ vaccination effect of TNFα and IL-12 plasmid DNA electrotransfer in a murine melanoma model
- Whole Blood Gene Expression Profiling in patients undergoing colon cancer surgery identifies differential expression of genes involved in immune surveillance, inflammation and carcinogenesis.
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