Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing
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Summary
Harnessing the migratory potential of MSCs by modulating their chemokine‐chemokine receptor interactions may be a powerful way to increase their ability to correct inherited disorders of mesenchymal tissues or facilitate tissue repair in vivo.
- Type
- review
- Published
- 2007-11-01
- Cited by
- 2,472
- References
- 125
- Access
- Open access
- OpenAlex
- https://openalex.org/W1965425745
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21930628
Keywords
Homing (biology), Mesenchymal stem cell, Biology, Cell biology, Chemokine receptor
References
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- Mesenchymal Stem Cells
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- Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny.
- Chemokines and leukocyte traffic
- Bone marrow cells regenerate infarcted myocardium
- Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells.
- Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors.
- Ectopic bone formation of human bone morphogenetic protein-2 gene transfected goat bone marrow-derived mesenchymal stem cells in nude mice.
- Lymphotactin: a cytokine that represents a new class of chemokine.
- Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
- The Dynamic in vivo Distribution of Bone Marrow-Derived Mesenchymal Stem Cells after Infusion
- Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells.
- Multipotential Mesenchymal Stem Cells Are Mobilized into Peripheral Blood by Hypoxia
- Mobilized bone marrow cells repair the infarcted heart, improving function and survival
Cited by
- Alpha 7 Subunit of nAChR Regulates Migration of Human Mesenchymal Stem Cells
- Влияние опиатных рецепторов на состояние митохондриальных дегидрогеназ мезенхимальных стволовых клеток крыс in vitro
- Adult mesenchymal stem cells: an innovative therapeutic for lung diseases.
- Adult stem cells and repair through granulation tissue.
- Mesenchymal stem cells arrest intervertebral disc degeneration through chondrocytic differentiation and stimulation of endogenous cells.
- Indirect co-culture with tenocytes promotes proliferation and mRNA expression of tendon/ligament related genes in rat bone marrow mesenchymal stem cells
- Directing bone marrow-derived stromal cell function with mechanics.
- Human multipotent mesenchymal stromal cells and their potential to differentiate into hepatocytes and beta cells
- CD73 and CD29 concurrently mediate the mechanically induced decrease of migratory capacity of mesenchymal stromal cells.
- Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models
- Adenovirus-mediated expression of the HO-1 protein within MSCs decreased cytotoxicity and inhibited apoptosis induced by oxidative stresses
- Isolation of the multipotent MSC subpopulation from human gingival fibroblasts by culturing on chitosan membranes.
- Mesenchymal stromal cells as a drug delivery system
- Mesenchymal Stem Cells and the Treatment of Conditions and Diseases: The Less Glittering Side of a Conspicuous Stem Cell for Basic Research
- Pre-treatment with IL-1β enhances the efficacy of MSC transplantation in DSS-induced colitis
- Three-Dimensional Spheroid-Cultured Mesenchymal Stem Cells Devoid of Embolism Attenuate Brain Stroke Injury After Intra-Arterial Injection
- Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system
- Metabolic labeling and click chemistry detection of glycoprotein markers of mesenchymal stem cell differentiation.
- Role of mesenchymal stem cells in cell life and their signaling.
- Novel approaches to lupus drug discovery using stem cell therapy. Role of mesenchymal-stem-cell-secreted factors
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