Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88 Dependent and Independent Signaling and is Reciprocally Modulated by LXR Activation

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Summary

It is concluded that C. pneumoniae facilitates foam cell formation via activation of both MyD88-dependent and MyD 88-independent pathways downstream of TLR2 and TLR4 signaling and that TLR3 is not involved in this process.

Type
article
Published
2008-11-15
Cited by
94
References
56
Access
Open access

Keywords

Chlamydia, Cell biology, Receptor, Chemistry, Signal transduction

References

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