Immunodominance of an Antiviral Cytotoxic T Cell Response Is Shaped by the Kinetics of Viral Protein Expression1

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Summary

It is proposed that CTL against early viral proteins swiftly interfere with virus replication, resulting in efficient protection and the observed absence of early CTL in persistent infections might not be the cause, but rather the consequence of viral persistence.

Type
article
Published
2003-11-15
Cited by
128
References
63
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Open access

Keywords

CTL*, Immunodominance, Lymphocytic choriomeningitis, Viral load, Virology

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