Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop

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Summary

It is demonstrated that the specific amino acids in the V3 loop of the HIV-1 envelope protein that determine cellular tropism also regulate chemokine coreceptor preference for cell entry by the virus.

Type
article
Published
1997-09-01
Cited by
302
References
38
Access
Open access

Keywords

Biology, V3 loop, Chemokine receptor, Tropism, CXCR4

References

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