Broad usage spectrum of G protein-coupled receptors as coreceptors by primary isolates of HIV.
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Summary
FPRL1 and GPR1 have the potential to work as significant HIV-1 coreceptors in vivo next to CCR5 and CXCR4 and it is found that CCR9B, CCR10, and XCR1 also work as novel HIV- 1 coreceptor.
- Type
- article
- Published
- 2009-04-27
- Cited by
- 74
- References
- 38
- OpenAlex
- https://openalex.org/W19307942
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24659196
Keywords
Computer science, Computer graphics (images)
References
- HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor
- Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene
- An Orphan G Protein-Coupled Receptor, GPR1, Acts as a Coreceptor To Allow Replication of Human Immunodeficiency Virus Types 1 and 2 in Brain-Derived Cells
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- Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
- Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop
- A new reporter cell line to monitor HIV infection and drug susceptibility in vitro.
- Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene.
- Evidence for the HIV-1 phenotype switch as a causal factor in acquired immunodeficiency
- The Promiscuous CC Chemokine Receptor D6 Is a Functional Coreceptor for Primary Isolates of Human Immunodeficiency Virus Type 1 (HIV-1) and HIV-2 on Astrocytes
- Increased Infectivity of HIV Type 1 Particles Bound to Cell Surface and Solid-Phase ICAM-1 and VCAM-1 through Acquired Adhesion Molecules LFA-1 and VLA-4
- Synthesis of Human Immunodeficiency Virus DNA In a Cell-to-Cell Transmission Model
- Establishment of a new system for determination of coreceptor usages of HIV based on the human glioma NP-2 cell line.
- Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: Implications for HIV primary infection
- STRL33, A Novel Chemokine Receptor–like Protein, Functions as a Fusion Cofactor for Both Macrophage-tropic and T Cell Line–tropic HIV-1
- Evolution of sequences encoding the principal neutralization epitope of human immunodeficiency virus 1 is host dependent, rapid, and continuous.
- Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT).
- Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural DNA.
- Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1.
Cited by
- Estudo da susceptibilidade do VIH-2 à inibição por moléculas inibidoras do co-recptor CCR5
- Estudi de l’evolució de l’envolta del VIH-1 en pacients infectats sotmesos a vacunació terapèutica amb virus autòleg inactivat
- Phenotypic Characteristics of Mucosally Transmitted HIV-1
- X4‐tropic human immunodeficiency virus IIIB utilizes CXCR4 as coreceptor, as distinct from R5X4‐tropic viruses
- Association of chemokine receptor gene variants with HIV‐1 genotype predicted tropism
- Activation of retrovirus spikes for membrane fusion
- Short communication: identification of the conformational requirement for the specificities of coreceptors for human and simian immunodeficiency viruses.
- Preclinical discovery and development of maraviroc for the treatment of HIV
- The magnitude of HIV-1 resistance to the CCR5 antagonist maraviroc may impart a differential alteration in HIV-1 tropism for macrophages and T-cell subsets.
- Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death
- Macrophage-assisted inflammation and pharmacological regulation of the cholinergic anti-inflammatory pathway.
- Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques
- The Regulation of Inflammatory Pathways and Infectious Disease of the Cervix by Seminal Fluid
- Macrophage‐tropic HIV‐1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5
- Identification of preferential CD4+ T-cell targets for HIV infection in the cervix
- Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection
- Role of Exonic Variation in Chemokine Receptor Genes on AIDS: CCRL2 F167Y Association with Pneumocystis Pneumonia
- HIV-1 Escape from the CCR5 Antagonist Maraviroc Associated with an Altered and Less-Efficient Mechanism of gp120-CCR5 Engagement That Attenuates Macrophage Tropism
- Primary Infection by a Human Immunodeficiency Virus with Atypical Coreceptor Tropism
- The CD8-Derived Chemokine XCL1/Lymphotactin Is a Conformation-Dependent, Broad-Spectrum Inhibitor of HIV-1
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