Adherens junction: molecular architecture and regulation.
Explore this paper's citation graph
Summary
The adherens junction is an element of the cell-cell junction in which cadherin receptors bridge the neighboring plasma membranes via their homophilic interactions, and elucidating the molecular architecture of the AJs and their regulatory mechanisms are crucial for understanding how the multicellular system is organized.
- Type
- article
- Published
- 2009-12-01
- Cited by
- 619
- References
- 129
- Access
- Open access
- OpenAlex
- https://openalex.org/W20457565
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:321119
Keywords
History
References
- Ultrastructure of the zonula adherens revealed by rapid-freeze deep-etching.
- p120 catenin associates with kinesin and facilitates the transport of cadherin–catenin complexes to intercellular junctions
- Diversification of epithelial adherens junctions with independent reductive changes in cadherin form: identification of potential molecular synapomorphies among bilaterians
- Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network
- Deconstructing the cadherin-catenin-actin complex.
- The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.
- Roles of nectins in cell adhesion, migration and polarization
- Dynein binds to β-catenin and may tether microtubules at adherens junctions
- Structure and function of desmosomes.
- E-cadherin mediated cell adhesion recruits SAP97 into the cortical cytoskeleton.
- The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.
- Microtubules regulate disassembly of epithelial apical junctions
- The p120 family of cell adhesion molecules.
- Separation Force Measurements Reveal Different Types of Modulation of E-cadherin-based Adhesion by Nectin-1 and -3*
- Afadin: A Novel Actin Filament–binding Protein with One PDZ Domain Localized at Cadherin-based Cell-to-Cell Adherens Junction
- Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled.
- aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization
- New mode of DNA binding of multi‐zinc finger transcription factors: δEF1 family members bind with two hands to two target sites
- Shroom induces apical constriction and is required for hingepoint formation during neural tube closure.
- Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis
Cited by
- Adherens junctions and cancer.
- Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions.
- Adherens junctions during cell migration.
- Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation
- Tetraspanin18 is a FoxD3-responsive antagonist of cranial neural crest epithelial-to-mesenchymal transition that maintains cadherin-6B protein
- A Network Study of Chinese Medicine Xuesaitong Injection to Elucidate a Complex Mode of Action with Multicompound, Multitarget, and Multipathway
- The morphological and molecular mechanisms of epithelial/endothelial-to-mesenchymal transition and its involvement in atherosclerosis.
- Adjustable viscoelasticity allows for efficient collective cell migration
- FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and target of anticancer therapy.
- Embryonic cell-cell adhesion: a key player in collective neural crest migration.
- Adherens Junction Assembly
- Identification of functional miRNA interactions in Malignant Melanoma progression
- Stability and dynamics of cell-cell junctions.
- Investigation into the cellular mechanisms underlying cell sorting by Eph receptors and ephrins
- The three-dimensional structure of the cadherin-catenin complex.
- The story of redundant catenins and their roles in cell-cell adhesion in the liver
- Maintenance of epidermal architecture by CLASP2 and p120-catenin
- Shroom3 and planar cell polarity couple apical constriction and convergent extension during neural tube morphogenesis
- DEVELOPMENTAL AND MOLECULAR FUNCTIONS OF PLAKOPHILIN-3
- Dynamics and regulation of epithelial adherens junctions: recent discoveries and controversies.