Proresolving Action of Docosahexaenoic Acid Monoglyceride in Lung Inflammatory Models Related to Cystic Fibrosis.
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Summary
MAG-DHA displays antiinflammatory properties and reduces mucin overexpression in Calu-3 cells and human bronchi untreated or treated with P. aeruginosa LPS, a finding consistent with the effects of resolvinD1, a known antiinflammatory mediator.
- Type
- article
- Published
- 2015-10-01
- Cited by
- 18
- References
- 39
- OpenAlex
- https://openalex.org/W1828269568
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24174470
Keywords
Docosahexaenoic acid, Cystic fibrosis, Action (physics), Lung, Medicine
References
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- Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis.
- Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B.
- Association of cystic fibrosis with abnormalities in fatty acid metabolism.
- Data Analysis and Statistics
- An overview of monitoring and supplementation of omega 3 fatty acids in cystic fibrosis.
- Current knowledge on fatty acids in cystic fibrosis.
- A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice.
- MAG‐EPA resolves lung inflammation in an allergic model of asthma
- Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.
- CPI-17 silencing-reduced responsiveness in control and TNF-alpha-treated human bronchi.
- RNA interference and ion channel physiology
- Resolvins and Protectins in Inflammation-Resolution
- Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease.
- The use of an intravenous fish oil emulsion enriched with omega-3 fatty acids in patients with cystic fibrosis.
- Effect of an 8-month treatment with omega-3 fatty acids (eicosapentaenoic and docosahexaenoic) in patients with cystic fibrosis.
- 19,20-EpDPE, a bioactive CYP450 metabolite of DHA monoacyglyceride, decreases Ca²⁺ sensitivity in human pulmonary arteries.
- Inflammation and infection in naive human cystic fibrosis airway grafts.
- Fatty Acid Supplementation Improves Respiratory, Inflammatory and Nutritional Parameters in Adults with Cystic Fibrosis
Cited by
- Can maternal DHA supplementation offer long-term protection against neonatal hyperoxic lung injury?
- Update on the spider and the fly: An extended commentary on “Oxidized LDL induced extracellular trap formation in human neutrophils via TLR-PKC-IRAK-MAPK and NADPH-Oxidase activation”
- Omega-3 PUFA docosahexaenoic acid decreases LPS-stimulated MUC5AC production by altering EGFR-related signaling in NCI-H292 cells.
- Rôle physiologique des époxy- et des polyhydroxy-éicosanoïdes dans les voies aériennes : résolution de l’inflammation et diminution de l’hyperréactivité bronchique.
- Novel n-3 PUFA monoacylglycerides of pharmacological and medicinal interest: Anti-inflammatory and anti-proliferative effects.
- Specialized Proresolving Mediators in Innate and Adaptive Immune Responses in Airway Diseases.
- The Efficacy of MAG-DHA for Correcting AA/DHA Imbalance of Cystic Fibrosis Patients
- Omega-3 polyunsaturated fatty acids as adjuvant therapy of colorectal cancer
- Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos
- Structural characterization of self-assemblies of new omega-3 lipids: docosahexaenoic acid and docosapentaenoic acid monoglycerides.
- Endocannabinoid Virodhamine is an Endogenous Inhibitor of Human Cardiovascular CYP2J2 Epoxygenase
- Emerging Class of Omega-3 Fatty Acid Endocannabinoids & Their Derivatives
- Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction.
- The role of essential fatty acids in cystic fibrosis and normalizing effect of fenretinide
- A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts
- Dual tobramycin and docosahexaenoic acid loaded nanoemulsions combating Pseudomonas aeruginosa-induced pulmonary infection.
- Fatty acid abnormalities in cystic fibrosis–the missing link for a cure?
- Selective Antiproliferative Effects of Marine Oils on Neuroblastoma Cells in 3D Cultures
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