Alternatively activated microglia and macrophages in the central nervous system.
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Summary
Cumulative evidence shows that microglia may undergo the alternative activation pathway, express M2-type markers and contribute to neuroprotection, and in the approaches available for its identification.
- Type
- review
- Published
- 2015-08-01
- Cited by
- 606
- References
- 412
- OpenAlex
- https://openalex.org/W1817666133
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9679437
Keywords
Microglia, Neuroprotection, Central nervous system, Neuroscience, Biology
References
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- In Vitro and In Vivo Models of Cerebral Ischemia Show Discrepancy in Therapeutic Effects of M2 Macrophages
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- Are “Resting” Microglia More “M2”?
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- Sex Steroids Control Neuroinflammatory Processes in the Brain: Relevance for Acute Ischaemia and Degenerative Demyelination
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- Macrophage-like suppressor cells in rats. II. Evidence for a quantitative rather than a qualitative change in tumour-bearer animals.
Cited by
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- The hypnotic bromovalerylurea ameliorates 6-hydroxydopamine-induced dopaminergic neuron loss while suppressing expression of interferon regulatory factors by microglia.
- Neuro-immune interactions across development: A look at glutamate in the prefrontal cortex.
- Pregnancy Vaccination with Gold Glyco-Nanoparticles Carrying Listeria monocytogenes Peptides Protects against Listeriosis and Brain- and Cutaneous-Associated Morbidities
- Microglial Activation in the Pathogenesis of Huntington’s Disease
- Microglia are continuously activated in the circumventricular organs of mouse brain.
- Exosomes Isolated From Human Umbilical Cord Mesenchymal Stem Cells Alleviate Neuroinflammation and Reduce Amyloid-Beta Deposition by Modulating Microglial Activation in Alzheimer’s Disease
- Re‐wiring regulatory cell networks in immunity by galectin–glycan interactions
- Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury
- Prenatal immune activation causes hippocampal synaptic deficits in the absence of overt microglia anomalies.
- Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway
- Late prenatal immune activation causes hippocampal deficits in the absence of persistent inflammation across aging
- Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells.
- Lack of NG2 exacerbates neurological outcome and modulates glial responses after traumatic brain injury
- Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins
- Enriched environment decreases microglia and brain macrophages inflammatory phenotypes through adiponectin-dependent mechanisms: Relevance to depressive-like behavior.
- Resolvin D1 and E1 promote resolution of inflammation in microglial cells in vitro.
- Modulators of microglia: a patent review
- TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice.
- Classical and Alternative Activation of Cyanobacterium Oscillatoria sp. Lipopolysaccharide-Treated Rat Microglia in vitro.
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