Re‐wiring regulatory cell networks in immunity by galectin–glycan interactions
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Summary
This work focuses on the emerging roles of galectins, a family of highly conserved glycan‐binding proteins in regulating the fate and function of regulatory immune cell populations, both of lymphoid and myeloid origins.
- Type
- review
- Published
- 2015-11-14
- Cited by
- 54
- References
- 161
- Access
- Open access
- OpenAlex
- https://openalex.org/W1544640024
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:35953293
Keywords
Galectin, Glycan, Cell biology, Immunity, Chemistry
References
- Evidence of a role for galectin‐1 in acute inflammation
- Galectin-8 Ameliorates Murine Autoimmune Ocular Pathology and Promotes a Regulatory T Cell Response
- Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate.
- Regulated expression of galectin-3, a multifunctional glycan-binding protein, in haematopoietic and non-haematopoietic tissues.
- Galectin-1 Regulates Tissue Exit of Specific Dendritic Cell Populations
- Dual roles of endogenous and exogenous galectin-1 in the control of testicular immunopathology
- Glioma‐derived galectin‐1 regulates innate and adaptive antitumor immunity
- Differential Response of Myeloid-Derived Suppressor Cells to the Nonsteroidal Anti-Inflammatory Agent Indomethacin in Tumor-Associated and Tumor-Free Microenvironments
- Transgenic Galectin-1 Induces Maturation of Dendritic Cells That Elicit Contrasting Responses in Naive and Activated T Cells1
- IL-10 deficiency blocks the ability of LPS to regulate expression of tolerance-related molecules on dendritic cells
- Regulation of secretion and surface expression of Mac-2, a galactoside-binding protein of macrophages.
- Galectin-3 Deficiency Reduces the Severity of Experimental Autoimmune Encephalomyelitis1
- A Novel Function for Galectin-1 at the Crossroad of Innate and Adaptive Immunity: Galectin-1 Regulates Monocyte/Macrophage Physiology through a Nonapoptotic ERK-Dependent Pathway1
- Galectin‐3 negatively regulates the frequency and function of CD4+CD25+Foxp3+ regulatory T cells and influences the course of Leishmania major infection
- Type 1 regulatory T cells: a new mechanism of peripheral immune tolerance
- Activated rat macrophages produce a galectin-1-like protein that induces apoptosis of T cells: biochemical and functional characterization.
- Proinflammatory stimuli induce galectin‐9 in human mesenchymal stromal cells to suppress T‐cell proliferation
- Anatomy of a Discovery: M1 and M2 Macrophages
- Differential Roles of Galectin-1 and Galectin-3 in Regulating Leukocyte Viability and Cytokine Secretion1
- Assembly, organization and regulation of cell-surface receptors by lectin-glycan complexes.
Cited by
- Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment.
- Galectin-9 Is a Suppressor of T and B Cells and Predicts the Immune Modulatory Potential of Mesenchymal Stromal Cell Preparations
- Expression of N-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels*
- Glycobiology simplified: diverse roles of glycan recognition in inflammation
- Shaping the Immune Landscape in Cancer by Galectin-Driven Regulatory Pathways.
- Cadherins Glycans in Cancer: Sweet Players in a Bitter Process.
- Functional Characteristics of the Gut Microbiome in C57BL/6 Mice Differentially Susceptible to Plasmodium yoelii
- TRIMs and Galectins globally cooperate and TRIM16 and Galectin-3 co-direct autophagy in endomembrane damage homeostasis
- Galectin-9: Diverse Roles in Hepatic Immune Homeostasis and Inflammation
- Expression et fonctions des galectines dans le cancer
- Functions of galectins as ‘self/non‐self’‐recognition and effector factors
- CXCR3.1 and CXCR3.2 Differentially Contribute to Macrophage Polarization in Teleost Fish
- Resolution of Cochlear Inflammation: Novel Target for Preventing or Ameliorating Drug-, Noise- and Age-related Hearing Loss
- Long‐term effects: Galectin‐1 and specific immunotherapy for allergic responses in the intestine
- Galectins in Intestinal Inflammation: Galectin-1 Expression Delineates Response to Treatment in Celiac Disease Patients
- Galectins at a glance
- Hypersialylation in Cancer: Modulation of Inflammation and Therapeutic Opportunities
- Comparative characterization of two galectins excreted-secreted from intestine-dwelling parasitic versus free-living females of the soil-transmitted nematode Strongyloides.
- Xanthohumol and 8-prenylnaringenin reduce type 2 diabetes–associated oxidative stress by downregulating galectin-3
- Surfaceome nanoscale organization and extracellular interaction networks.
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