Regulatory T cells in systemic lupus erythematosus
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Summary
Findings from murine models and ex vivo experiments are summarized, which provide insights into the mechanisms that result in the breakdown of tolerance in systemic lupus erythematosus and include recent findings about Treg‐cell subsets and their markers in human SLE.
- Type
- review
- Published
- 2015-02-01
- Cited by
- 257
- References
- 123
- OpenAlex
- https://openalex.org/W1810971862
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40275709
Keywords
Biology, Immunology
References
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- X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
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- CD161 expression characterizes a sub-population of human regulatory T cells that produces IL-17 in a STAT3 dependent manner
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- IL-17+ Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer
- TGF-β-Mediated Suppression by CD4+CD25+ T Cells Is Facilitated by CTLA-4 Signaling
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- Control of tissue‐localized immune responses by human regulatory T cells
- Self-antigen driven activation induces instability of regulatory T cells during an inflammatory autoimmune response
Cited by
- Genetics and novel aspects of therapies in systemic lupus erythematosus.
- Control of tissue‐localized immune responses by human regulatory T cells
- The cAMP response element modulator (CREM) regulates TH2 mediated inflammation
- The Pathology of T Cells in Systemic Lupus Erythematosus
- Autoimmunity in 2012
- Stem Cell Therapy in Autoimmune Rheumatic Diseases: a Comprehensive Review
- Involvement of the IL-23/IL-17 axis and the Th17/Treg balance in the pathogenesis and control of autoimmune arthritis
- Both Treg cells and Tconv cells are defective in the Myasthenia gravis thymus: roles of IL-17 and TNF-α.
- Common variable immunodeficiency: crossroads between infections, inflammation and autoimmunity.
- Enhanced killing activity of regulatory T cells ameliorates inflammation and autoimmunity.
- Potential roles for CD8(+) T cells in rheumatoid arthritis.
- Major Pathogenic Steps in Human Lupus Can be Effectively Suppressed by Nucleosomal Histone Peptide Epitope-Induced Regulatory Immunity
- Impaired expansion of regulatory T cells in a neonatal thymectomy-induced autoimmune mouse model.
- Comparative analysis of rosacea and cutaneous lupus erythematosus: histopathologic features, T-cell subsets, and plasmacytoid dendritic cells.
- The association of CD40 polymorphisms with CD40 serum levels and risk of systemic lupus erythematosus
- Regulatory T lymphocytes in myocardial infarction: A promising new therapeutic target.
- Abul Abbas: an epitome of scholarship.
- Systemic lupus erythematosus
- Glucose oxidation is critical for CD4+ T cell activation in a mouse model of systemic lupus erythematosus
- Expression of TLR-7, MyD88, NF-kB, and INF-α in B Lymphocytes of Mayan Women with Systemic Lupus Erythematosus in Mexico
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