How tumour necrosis factor blockers interfere with tuberculosis immunity
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Summary
This review summarizes some of the reported effects of TNF blockers on immune cell responses in the context of the observed clinical data on TB reactivation in patients on anti‐TNF therapy.
- Type
- review
- Published
- 2010-07-01
- Cited by
- 289
- References
- 93
- Access
- Open access
- OpenAlex
- https://openalex.org/W1786795173
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8425863
Keywords
Immunology, Adalimumab, Etanercept, Infliximab, Medicine
References
- Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor alpha-expressing cells: comparison among infliximab, etanercept, and adalimumab.
- Corynebacterium parvum- and Mycobacterium bovis bacillus Calmette-Guerin-induced granuloma formation is inhibited in TNF receptor I (TNF-RI) knockout mice and by treatment with soluble TNF-RI.
- Measuring Autophagy in Macrophages
- Synergy between individual tumor necrosis factor-dependent functions determines granuloma performance for controlling Mycobacterium tuberculosis infection
- Pathogenic Mycobacterium tuberculosis evades apoptosis of host macrophages by release of TNF-R2, resulting in inactivation of TNF-alpha.
- Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages.
- Production of TNF-alpha, IL-6 and TGF-beta, and expression of receptors for TNF-alpha and IL-6, during murine Mycobacterium avium infection.
- Mycobacterium tuberculosis Phagosome Maturation Arrest: Selective Targeting of PI3P‐Dependent Membrane Trafficking
- Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease
- Transmembrane TNF Induces an Efficient Cell-Mediated Immunity and Resistance to Mycobacterium bovis Bacillus Calmette-Guérin Infection in the Absence of Secreted TNF and Lymphotoxin-α1
- Influence of Bacillus Calmette‐Guèrin vaccination at birth and 2 months old age on the peripheral blood T‐cell subpopulations [gamma/delta (γδ) and alpha‐beta (αβ) T cell]
- Infliximab downregulates interferon-gamma production in activated gut T-lymphocytes from patients with Crohn's disease.
- Tumor necrosis factor signaling
- NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy.
- Blocking TNF in vitro with infliximab determines the inhibition of expansion and interferon gamma production of Vgamma9/Vdelta2 T lymphocytes from patients with active rheumatoid arthritis. A role in the susceptibility to tuberculosis?
- TNF-dependent BALB/c murine macrophage apoptosis following Mycobacterium tuberculosis infection inhibits bacillary growth in an IFN-gamma independent manner.
- Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factor-α-induced cell death in MCF-7 cells
- Inhibition of autophagy abrogates tumour necrosis factor α induced apoptosis in human T‐lymphoblastic leukaemic cells
- Adalimumab induces apoptosis of human monocytes: a comparative study with infliximab and etanercept
- CD4(+)CD25(+)FoxP3(+) regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease.
Cited by
- Active Tuberculosis Risk With Tumor Necrosis Factor Inhibitors After Treating Latent Tuberculosis
- Evaluation of golimumab for the treatment of patients with active rheumatoid arthritis
- Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10+ Th17 CD4 T-cells differentiate latent from active tuberculosis
- Evaluation of LMP-420: A Novel, Nontoxic Drug with Anti-Inflammatory Properties and Therapeutic Potential for CLL
- Innovation in Vaccinology
- M.tb Killing by Macrophage Innate Immune Mechanisms: A Dissertation
- The death‐promoting molecule tumour necrosis factor‐related apoptosis inducing ligand (TRAIL) is not required for the development of peripheral lymphopenia or granuloma necrosis during infection with virulent Mycobacterium avium
- Mycobacterium poriferae infection in a psoriasis patient on anti-TNF-α therapy.
- Views of immunology: effector T cells
- Latent tuberculosis infection detection and active tuberculosis prevention in patients receiving anti‐TNF therapy: an Italian nationwide survey
- Mycobacterium marinum infection.
- Risk of infections of biological therapies with accent on inflammatory bowel disease.
- Cellular and Molecular Connections between Autophagy and Inflammation
- Receptor‐mediated recognition of mycobacterial pathogens
- Role of autophagy in the pathogenesis of multiple sclerosis
- A clinical and health economical observational study of anti-tumor necrosis factor therapy in the treatment of rheumatoid arthritis in Finland
- Tumor necrosis factor‐α can induce Langhans‐type multinucleated giant cell formation derived from myeloid dendritic cells
- Assessment of pulmonary function in rheumatoid arthritis patients attending Rheumatology Clinics in Nairobi
- Autophagy Regulates IL-23 Secretion and Innate T Cell Responses through Effects on IL-1 Secretion
- Early dynamics of T helper cell cytokines and T regulatory cells in response to treatment of active Mycobacterium tuberculosis infection
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