The death‐promoting molecule tumour necrosis factor‐related apoptosis inducing ligand (TRAIL) is not required for the development of peripheral lymphopenia or granuloma necrosis during infection with virulent Mycobacterium avium
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Summary
It is found that TRAIL‐deficient mice still developed splenic lymphopenia during disseminated infection or granuloma necrosis during low‐dose infections while exhibiting slightly increased susceptibility to M. avium‐induced lymph Openia.
- Type
- article
- Published
- 2011-06-01
- Cited by
- 6
- References
- 41
- Access
- Open access
- OpenAlex
- https://openalex.org/W1513878563
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11142292
Keywords
Biology, Spleen, Tumor necrosis factor alpha, Immunology, Immune system
References
- Mechanisms of HIV-associated lymphocyte apoptosis.
- Enhanced Proliferation and Increased IFN-γ Production in T Cells by Signal Transduced Through TNF-Related Apoptosis-Inducing Ligand1
- Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo
- Lymphocyte apoptosis in acute respiratory syncytial virus bronchiolitis
- IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression.
- IFN-gamma enhances TRAIL-induced apoptosis through IRF-1.
- Anergy, IFN-gamma production, and apoptosis in terminal infection of mice with Mycobacterium avium.
- Characterization of the Deregulated Immune Activation Occurring at Late Stages of Mycobacterial Infection in TNF-Deficient Mice1
- How tumour necrosis factor blockers interfere with tuberculosis immunity
- CD40 is required for the optimal induction of protective immunity to Mycobacterium avium
- Apoptosis of Th1‐like cells in experimental tuberculosis (TB)
- CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis.
- Genetic control of immune‐mediated necrosis of Mycobacterium avium granulomas
- Death ligand‐mediated apoptosis in HIV infection
- Antiviral response by natural killer cells through TRAIL gene induction by IFN–α/β
- Human herpesvirus 7 induces the functional up-regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) coupled to TRAIL-R1 down-modulation in CD4(+) T cells.
- CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?
- Blocking TRAIL-DR5 signaling with soluble DR5 reduces delayed neuronal damage after transient global cerebral ischemia.
- Characterization of the in vivo function of TNF‐α‐related apoptosis‐inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene‐deficient mice
- TRAIL receptor signalling and modulation: Are we on the right TRAIL?
Cited by
- Lack of the Transcription Factor Hypoxia-Inducible Factor 1α (HIF-1α) in Macrophages Accelerates the Necrosis of Mycobacterium avium-Induced Granulomas
- Distinct roles of TNF-related apoptosis-inducing ligand (TRAIL) in viral and bacterial infections: from pathogenesis to pathogen clearance
- HIF-1α relevance in necrosis of mycobacterium avium-induced granulomas
- Toxoplasma gondii infection reduces serum progesterone levels and adverse effects at the maternal‐foetal interface
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