Evaluation of golimumab for the treatment of patients with active rheumatoid arthritis
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Summary
This review summarizes published data on the clinical efficacy and safety for golimumab (including its pharmacodynamic and pharmacokinetic characteristics) from multiple global phase III and Japanese phase II/III clinical trials.
- Type
- review
- Published
- 2016-02-15
- Cited by
- 9
- References
- 48
- OpenAlex
- https://openalex.org/W2290192736
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:32743521
Keywords
Golimumab, Rheumatoid arthritis, Medicine, Methotrexate, Pharmacokinetics
References
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- [Pharmacological and clinical profile of golimumab (Simponi®)].
- High Resolution Mapping of the Binding Site on Human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and Design of IgG1 Variants with Improved Binding to the FcγR*
- How tumour necrosis factor blockers interfere with tuberculosis immunity
- Golimumab, a human anti-tumor necrosis factor alpha monoclonal antibody, injected subcutaneously every four weeks in methotrexate-naive patients with active rheumatoid arthritis: twenty-four-week results of a phase III, multicenter, randomized, double-blind, placebo-controlled study of golimumab bef
- The benefit/risk profile of TNF-blocking agents: findings of a consensus panel.
- The IgG Fc receptor family
- Pharmacology of TNF blockade in rheumatoid arthritis and other chronic inflammatory diseases.
- Comparisons of affinities, avidities, and complement activation of adalimumab, infliximab, and etanercept in binding to soluble and membrane tumor necrosis factor.
- Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α
- Golimumab pharmacokinetics after repeated subcutaneous and intravenous administrations in patients with rheumatoid arthritis and the effect of concomitant methotrexate: an open-label, randomized study.
- High-avidity human IgG kappa monoclonal antibodies from a novel strain of minilocus transgenic mice.
- Elimination mechanisms of therapeutic monoclonal antibodies.
- Transcytosis and catabolism of antibody
- The effects of golimumab on radiographic progression in rheumatoid arthritis: results of randomized controlled studies of golimumab before methotrexate therapy and golimumab after methotrexate therapy.
- Human antibodies from transgenic animals
- Antibody pharmacokinetics and pharmacodynamics.
- Effects of hydroxychloroquine and sulphasalazine on progression of joint damage in rheumatoid arthritis.
- Interstitial lung disease induced or exacerbated by TNF-targeted therapies: analysis of 122 cases.
- Golimumab in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy: Results Through 2 Years of the GO-FORWARD Study Extension
Cited by
- ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Soluble immune effector molecules [I]: anti-tumor necrosis factor-α agents).
- Dose Adjustment of Methotrexate Administered Concomitantly with Golimumab for Rheumatoid Arthritis in Japanese Real-World Clinical Settings
- Rheumatoid arthritis: advances in treatment strategies
- Persistence and Safety of Golimumab in Elderly Patients with Rheumatoid Arthritis and Renal Dysfunction in a Real-World Setting
- Trends in the Epidemiology of Pneumocystis Pneumonia in Immunocompromised Patients without HIV Infection
- Safety and Efficacy of Golimumab in Rheumatoid Arthritis: A Prospective, Multicenter, Real-World Study from India
- Abatacept, Golimumab, and Sarilumab as Selected Bio-Originator Disease-Modifying Antirheumatic Drugs with Diverse Mechanisms of Action in Their Current Use in Treatment
- Efficacy and Safety of Biosimilar AVT05 Versus Reference Product Golimumab in Combination with Methotrexate in Moderate-to-Severe Rheumatoid Arthritis: 52-Week Results of a Randomized, Parallel-Group, Double-Blind Study
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