The fatty acid oxidation product 15-A3t-Isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation
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- Type
- article
- Published
- 2011-09-23
- Cited by
- 30
- References
- 71
- OpenAlex
- https://openalex.org/W1720612225
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31910792
Keywords
Chemistry, Lipid peroxidation, Proinflammatory cytokine, Biochemistry, Carnosic acid
References
- The beneficial effects of omega-3 fatty acids: cardiovascular disease and neurodevelopment.
- Omega-3 Fatty Acids in Inflammation and Autoimmune Diseases
- PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
- Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress.
- Inflammation and Atherosclerosis
- Rapid de‐esterification and loss of eicosapentaenoic acid from rat brain phospholipids: an intracerebroventricular study
- Foam cell formation containing lipid droplets enriched with free cholesterol by hyperlipidemic serum.
- Regulation of M-CSF expression by M-CSF: role of protein kinase C and transcription factor NF kappa B.
- Mechanisms Underlying Inflammation in Neurodegeneration
- NF-kappaB activation by reactive oxygen species: fifteen years later.
- Prostaglandins and other lipid mediators in Alzheimer's disease.
- Formation of F-ring Isoprostane-like Compounds (F3-Isoprostanes) in Vivo from Eicosapentaenoic Acid*
- n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells.
- The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells.
- Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
- Oxidized omega-3 fatty acids inhibit pro-inflammatory responses in glomerular endothelial cells.
- Electrophilic Cyclopentenone Neuroprostanes Are Anti-inflammatory Mediators Formed from the Peroxidation of the ω-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid*
- n-3 fatty acids: Antiatherosclerotic effects
- Unsaturated fatty acids and their oxidation products stimulate CD36 gene expression in human macrophages.
- Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes) in Vivo from Eicosapentaenoic Acid*
Cited by
- Non-enzymatic cyclic oxygenated metabolites of omega-3 polyunsaturated fatty acid: Bioactive drugs?
- Fish oil supplements in New Zealand are highly oxidised and do not meet label content of n-3 PUFA
- Non-enzymatic cyclic oxygenated metabolites of adrenic, docosahexaenoic, eicosapentaenoic and α-linolenic acids; bioactivities and potential use as biomarkers.
- Lipid Profiling following Intake of the Omega 3 Fatty Acid DHA Identifies the Peroxidized Metabolites F4-Neuroprostanes as the Best Predictors of Atherosclerosis Prevention
- First total synthesis of labeled EPA and DHA-derived A-type cyclopentenone isoprostanoids: [D2]-15-A3t-IsoP and [D2]-17-A4t-NeuroP
- Lipids promote survival, proliferation, and maintenance of differentiation of rat liver sinusoidal endothelial cells in vitro.
- Pros and cons of fatty acids in bone biology.
- Oxidation of Marine Omega-3 Supplements and Human Health
- Isoprostanes and 4-Hydroxy-2-nonenal: Markers or Mediators of Disease? Focus on Rett Syndrome as a Model of Autism Spectrum Disorder
- Dietary Effects of Oxidized Eicosapentaenoic Acid (EPA) and Intact EPA on Hepatic Steatosis Induced by a High-sucrose Diet and Liver-X-receptor α Agonist in Mice.
- Studies on Nutraceutical Properties of Modified Fatty Acids by Autoxidation and Lactic Acid Bacterial Metabolism
- Vitamin E supplementation modulates the biological effects of omega-3 fatty acids in naturally aged rats
- Chemistry and biology of ω-3 PUFA peroxidation-derived compounds.
- Short-time UVA exposure to human keratinocytes instigated polyunsaturated fatty acid without inducing lipid peroxidation
- Addition of omega-3 fatty acid and coenzyme Q10 to statin therapy in patients with combined dyslipidemia
- Insight into the contribution of isoprostanoids to the health effects of omega 3 PUFAs.
- Role of lipid mediators in the regulation of oxidative stress and inflammatory responses in dairy cattle.
- Isoprostanes, neuroprostanes and phytoprostanes: An overview of 25years of research in chemistry and biology.
- Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages
- Biological activities of non-enzymatic oxygenated metabolites of polyunsaturated fatty acids (NEO-PUFAs) derived from EPA and DHA: New anti-arrhythmic compounds?
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