Initial sequence of the chimpanzee genome and comparison with the human genome
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Summary
It is found that the patterns of evolution in human and chimpanzee protein-coding genes are highly correlated and dominated by the fixation of neutral and slightly deleterious alleles.
- Type
- article
- Published
- 2005-09-01
- Cited by
- 2,345
- References
- 188
- Access
- Open access
- OpenAlex
- https://openalex.org/W1689369637
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2638825
Keywords
Biology, Genome, Genetics, Human genome, Evolutionary biology
References
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- Quantitative estimates of sequence divergence for comparative analyses of mammalian genomes.
- DNA sequence and comparative analysis of chimpanzee chromosome 22
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- Computational biology
- High genomic deleterious mutation rates in hominids
- Using CLUSTAL for multiple sequence alignments.
- Great ape DNA sequences reveal a reduced diversity and an expansion in humans
- Evolution by nearly-neutral mutations
- The proteins of linked genes evolve at similar rates
- Unexpectedly similar rates of nucleotide substitution found in male and female hominids
- Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region. Molecular cloning, exon-intron structure, composite retroposon, and breakpoint of gene duplication.
- A Human-Specific Gene in Microglia
- Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays
- Genetic basis of human brain evolution: accelerating along the primate speedway.
- Cultures in chimpanzees
- ICEBERG: a novel inhibitor of interleukin-1beta generation.
Cited by
- Genetics of Multiple Sclerosis
- Large-scale methods in computational genomics
- Structure-based prediction of insertion-site preferences of transposons into chromosomes
- Intra- and interindividual epigenetic variation in human germ cells.
- Structural divergence between the human and chimpanzee genomes
- The medaka draft genome and insights into vertebrate genome evolution
- Modelling Down syndrome.
- A prominent role for segmental duplications in modeling eukaryotic genomes.
- Pervasive Natural Selection in the Drosophila Genome?
- The evolution of mammalian chemokine genes.
- A Comprehensive Map of Mobile Element Insertion Polymorphisms in Humans
- Abundance of ultramicro inversions within local alignments between human and chimpanzee genomes
- Origins and Genetic Legacy of Neolithic Farmers and Hunter-Gatherers in Europe
- Shape-based alignment of genomic landscapes in multi-scale resolution
- Selective Constraint on Copy Number Variation in Human Piwi-Interacting RNA Loci
- Ancient humans and the origin of modern humans.
- Multispecies Coalescent Analysis of the Early Diversification of Neotropical Primates: Phylogenetic Inference under Strong Gene Trees/Species Tree Conflict
- Evolutionary impacts of DNA methylation on vertebrate genomes
- Identification of Deleterious and Disease Alleles in a General Population and Preterm Labor Patients
- Zebrafish models for functional and toxicological screening of nanoscale drug delivery systems: promoting preclinical applications
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