Exosome-mediated microenvironment dysregulation in leukemia.
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Summary
Recent works that decipher the normal hematopoietic niche cellular components are summarized and how the leukemia-transformed niche contributes to hematological malignances is described.
- Type
- review
- Published
- 2016-03-01
- Cited by
- 74
- References
- 78
- Access
- Open access
- OpenAlex
- https://openalex.org/W1683650673
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37268472
Keywords
Niche, Microvesicles, Biology, Leukemia, Haematopoiesis
References
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- Mobilization of hematopoietic stem and leukemia cells
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- Glypican1 identifies cancer exosomes and facilitates early detection of cancer
- CXCL12-producing vascular endothelial niches control acute T cell leukemia maintenance
- Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
- Exosomes Derived from Burkitt’s Lymphoma Cell Lines Induce Proliferation, Differentiation, and Class-Switch Recombination in B Cells
- Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes).
- Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells
- Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts.
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
- Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development.
- Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro
- Identification of the haematopoietic stem cell niche and control of the niche size
- Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance.
- Targeting of CD44 eradicates human acute myeloid leukemic stem cells
- Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
Cited by
- The impact of inflammation and cytokine expression of PM2.5 in AML.
- The emerging roles of exosomes in leukemogeneis
- Exosomal miR‐486 regulates hypoxia‐induced erythroid differentiation of erythroleukemia cells through targeting Sirt1
- The emerging roles of tumor-derived exosomes in hematological malignancies
- Exosomes carrying immunoinhibitory proteins and their role in cancer
- Mitochondrial Transfer in the Leukemia Microenvironment.
- Extracellular vesicles in leukemia.
- Understanding the bone marrow microenvironment in hematologic malignancies: a focus on chemokine, integrin, and extracellular vesicle signaling
- Exosome and mesenchymal stem cell cross-talk in the tumor microenvironment
- Nanoparticles—Emerging Potential for Managing Leukemia and Lymphoma
- Extracellular vesicles in hematological malignancies
- Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures
- Gold nanoparticles for nanotheranostics in leukemia – Addressing Chronic Myeloid Leukemia
- Modifying exosome release in cancer therapy: How can it help?
- Acute myeloid leukemia remodels endosteal vascular niche into a leukemic niche.
- Alteration of cellular and immune‐related properties of bone marrow mesenchymal stem cells and macrophages by K562 chronic myeloid leukemia cell derived exosomes
- MicroRNAs in Autoimmunity and Hematological Malignancies
- Leukemia-derived exosomes and cytokines pave the way for entry into the brain
- Stem Cells & Extracellular Vesicles in Physiology & Disease.
- Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
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