Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities

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Summary

Recent insights into the cellular and molecular determinants of the normal HSC niche are reviewed and how genetic changes in stromal cells and leukemia-induced BM niche remodeling contribute to blood malignancies are described.

Type
article
Published
2015-03-05
Cited by
408
References
118
Access
Open access

Keywords

Physics, Humanities, Forestry, Geography, Philosophy

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