Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

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Summary

The results show that both systemic and local T-cell activation can lead to OPGL production and subsequent bone loss, and they provide a novel paradigm for T cells as regulators of bone physiology.

Type
article
Published
1999-11-18
Cited by
1,299
References
26

Keywords

Osteoprotegerin, Osteoclast, Bone remodeling, Inflammation, Arthritis

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