Bone loss in the spondyloarthropathies: role of osteoclast, RANKL, RANK and OPG in the spondyloarthropathies.
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Summary
This chapter will review the recent literature on the role of osteoclasts and the RANKL/OPG system in the various spondyloarthropathies and try to formulate a hypothesis for the possible mechanism of bone loss in this group of inflammatory rheumatic disease.
- Type
- review
- Published
- 2009-01-01
- Cited by
- 20
- References
- 102
- OpenAlex
- https://openalex.org/W16251345
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9338269
Keywords
RANKL, Osteoclast, Bone resorption, RANK Ligand, Medicine
References
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- Imbalance of Osteoclastogenesis‐Regulating Factors in Patients With Celiac Disease
- Malignant Autosomal Recessive Osteopetrosis Caused by Spontaneous Mutation of Murine Rank
- The prevalence of vertebral fractures in mild ankylosing spondylitis and their relationship to bone mineral density.
- Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis
- Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation
Cited by
- IL-4 Modulates Macrophage Polarization in Ankylosing Spondylitis
- NSAIDs can have adverse effects on bone healing.
- Mechanisms of tissue damage in arthritis
- hRpn13, a newly identified component of the 19S particle, regulates proliferation, differentiation, and function in the human osteoblast-like cell line MG63
- Pathogenesis of axial spondyloarthropathy in a network perspective
- Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells
- Insights into the pathogenesis of axial spondyloarthropathy from network and pathway analysis
- Modulation of Signaling Molecules by Human Leucocyte Antigen B27; Special Reference to STAT1
- Why platelet-rich plasma failed to promote bone healing in combination with a biphasic synthetic graft material in bone defects: a critical comment.
- Low level laser therapy accelerates bone healing in spinal cord injured rats.
- Echinocystic acid inhibits RANKL-induced osteoclastogenesis by regulating NF-κB and ERK signaling pathways.
- Frequency of low bone mineral density in spondyloarthropathy presenting at a tertiary care hospital.
- Pathophysiology of hemophilic arthropathy and potential targets for therapy
- Osteoconductive properties of two different bioactive glass forms (powder and fiber) combined with collagen
- The multifaceted link between inflammation and human diseases
- The impact of osteoporosis in patients with ankylosing spondylitis and its relationship to physical activity
- In vitro and in vivo genotoxicity and cytotoxicity analysis of protein extract from Aplysina fulva sponges
- C-C Motif Chemokine Ligand 5 (CCL5) Promotes Irradiation-Evoked Osteoclastogenesis
- ASSESSMENT OF THE RATE OF MINERAL DENSITY IN BONES AND THE FACTORS CONTRIBUTING TO LOW BONE DENSITY IN PEOPLE SUFFERING FROM SPONDYLOARTHROPATHIES
- Erratum to: hRpn13, a newly identified component of the 19S particle, regulates proliferation, differentiation, and function in the human osteoblast-like cell line MG63
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