Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1.
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Summary
It is shown that although Gram-negative bacteria can activate the type I IFN pathway throughTLR4, the intracellular Gram-positive bacterium Listeria monocytogenes (LM) can do so independently of TLR4 and TLR2.
- Type
- article
- Published
- 2005-02-01
- Cited by
- 73
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1673881514
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19630528
Keywords
TANK-binding kinase 1, TLR2, Signal transduction, Biology, Cell biology
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