Gene Expression Analysis of Macrophages That Facilitate Tumor Invasion Supports a Role for Wnt-Signaling in Mediating Their Activity in Primary Mammary Tumors
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Summary
It is conjecture that invasive TAMs link angiogenesis and tumor invasion and that Wnt-signaling plays a role in mediating their activity.
- Type
- article
- Published
- 2009-12-16
- Cited by
- 236
- References
- 72
- Access
- Open access
- OpenAlex
- https://openalex.org/W1663505974
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28699474
Keywords
Biology, Wnt signaling pathway, Cancer research, Angiogenesis, Intravasation
References
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- Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer.
- ONCOMINE: a cancer microarray database and integrated data-mining platform.
- Risk for Subsequent Cancer after Diagnosis of Basal-Cell Carcinoma: A Population-Based, Epidemiologic Study
- CSF-1 and its receptor in ovarian, endometrial and breast cancer.
- A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors
Cited by
- New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers.
- Design and data analysis of kinome microarrays
- Investigating Gp96 Biology and its Macrophage-Intrinsic Role in Colitis-Associated Colon Tumorigenesis
- The Embryonic Protein Nodal Supports Metastatic Phenotypes in Breast Cancer
- Macrophages: Biology and Role in the Pathology of Diseases
- Cellular microenvironment in Burkitt’s lymphoma : gene expression profiling of tumour-associated macrophages in situ
- Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer.
- Microenvironments Dictating Tumor Cell Dormancy
- Immunology in the clinic review series; focus on cancer: tumour‐associated macrophages: undisputed stars of the inflammatory tumour microenvironment
- Metastasis Suppressor Genes: At the Interface Between the Environment and Tumor Cell Growth
- From a pathologist's point of view: Histiocytic cells in Hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma.
- Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro
- Human breast cancer cells educate macrophages toward the M2 activation status
- Mechanisms Driving Macrophage Diversity and Specialization in Distinct Tumor Microenvironments and Parallelisms with Other Tissues
- Role of tumor-associated macrophages in the progression of hepatocellular carcinoma
- The tumor microenvironment at a glance
- Tumor microenvironment: a main actor in the metastasis process
- Tumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L
- Angiogenic Activity of Breast Cancer Patients’ Monocytes Reverted by Combined Use of Systems Modeling and Experimental Approaches
- Macrophage iron homeostasis and polarization in the context of cancer.
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