ONCOMINE: a cancer microarray database and integrated data-mining platform.
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Summary
ONCOMINE is presented, a cancer microarray database and web-based data-mining platform aimed at facilitating discovery from genome-wide expression analyses and novel biomarkers and therapeutic targets are discovered.
- Type
- article
- Published
- 2004-01-01
- Cited by
- 3,467
- References
- 47
- Access
- Open access
- OpenAlex
- https://openalex.org/W1977918192
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1582696
Keywords
Microarray databases, Microarray analysis techniques, Computational biology, DNA microarray, Biology
References
- HER2 Is Frequently Over‐expressed in Ovarian Clear Cell Adenocarcinoma: Possible Novel Treatment Modality Using Recombinant Monoclonal Antibody against HER2, Trastuzumab
- Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats.
- Show me the data!
- Minimum information about a microarray experiment (MIAME)—toward standards for microarray data
- Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer.
- Expression profiling reveals hepsin overexpression in prostate cancer.
- Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis.
- Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas.
- Prostasin, a potential serum marker for ovarian cancer: identification through microarray technology.
- The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma.
- Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.
- Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer.
- Diversity of gene expression in adenocarcinoma of the lung
- Gene-expression profiles predict survival of patients with lung adenocarcinoma
- Predicting hepatitis B virus–positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
- From biological databases to platforms for biomedical discovery.
- TTD: Therapeutic Target Database
- alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer.
- Delineation of prognostic biomarkers in prostate cancer
- Identifying distinct classes of bladder carcinoma using microarrays
Cited by
- Platforms for biomarker analysis using high-throughput approaches in genomics, transcriptomics, proteomics, metabolomics, and bioinformatics.
- Defining aggressive prostate cancer using a 12-gene model.
- Regulation of cell proliferation by the antizyme inhibitor: evidence for an antizyme-independent mechanism
- Application of Bayesian networks for inferring cause-effect relations from gene expression profiles of cancer versus normal cells.
- Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer.
- Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library.
- The La Autoantigen Is a Malignancy-Associated Cell Death Target That Is Induced by DNA-Damaging Drugs
- GOLPH2 protein expression as a novel tissue biomarker for prostate cancer: implications for tissue-based diagnostics
- Mitotic chromosomal instability and cancer: mouse modelling of the human disease
- Proteogenomic studies in epithelial ovarian cancer: established knowledge and future needs.
- Identification of MST1/STK4 and SULF1 Proteins as Autoantibody Targets for the Diagnosis of Colorectal Cancer by Using Phage Microarrays*
- Alignment of gene expression profiles from test samples against a reference database: New method for context-specific interpretation of microarray data
- Cathepsin C is a tissue-specific regulator of squamous carcinogenesis
- Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome
- Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors
- TRPM7 channel inhibition mediates midazolam-induced proliferation loss in human malignant glioma
- Salivary gland anlage tumor: molecular profiling sheds light on a morphologic question.
- Computational analysis of the evolutionarily conserved Missing In Metastasis/Metastasis Suppressor 1 gene predicts novel interactions, regulatory regions and transcriptional control
- Hypermethylated and downregulated MEIS2 are involved in stemness properties and oxaliplatin‐based chemotherapy resistance of colorectal cancer
- Molecular Screening for Target Discovery in Cancer
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