Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis

Keywords

Warburg effect, Lipogenesis, Liver X receptor, Nuclear receptor, Corepressor

References

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Cited by

• Anticancer drugs: Repressing LXRs to starve cancer達治 尾立, 淳子 飯岡, 修一 大沼 — 2015
• Are Synthetic Compounds that Silence the Liver-X-Receptor the Next Generation of Anti-cancer Drugs?Knut R. Steffensen — 2015
• The emerging roles of liver X receptors and their ligands in cancerChin‐Yo Lin, Lise‐Lotte Vedin, Knut R. Steffensen — 2016
• A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosisAnthony Arlia‐Ciommo, Veronika Svistkova, Sadaf Mohtashami — 2015
• Cholesterol metabolites and tumor microenvironment: the road towards clinical translationLaura Raccosta, Raffaella Fontana, Gianfranca Corna — 2015
• Destabilization of the torsioned conformation of a ligand side chain inverts the LXRβ activity.Lautaro D. Álvarez, María V. Dansey, Diego Y. Grinman — 2015
• Altered glycometabolism affects both clinical features and prognosis of triple-negative and neoadjuvant chemotherapy-treated breast cancerTieying Dong, Xinmei Kang, Zhaoliang Liu — 2016
• The Warburg Effect: How Does it Benefit Cancer Cells?Maria V. Liberti, Jason W. Locasale — 2016
• Lipid metabolic reprogramming in cancer cellsSadia Beloribi‐Djefaflia, Sophie Vasseur, Fabienne Guillaumond — 2016
• Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01Kotohiko Kimura, Ru Chih C. Huang — 2016
• Fatty acids and breast cancer: Make them on site or have them deliveredWilliam B. Kinlaw, Paul W. Baures, Leslie Lupien — 2016
• Modulation of glycolysis and lipogenesis by novel PI3K selective molecule represses tumor angiogenesis and decreases colorectal cancer growth.Aashiq Hussain, Asif Khurshid Qazi, Nagaraju Mupparapu — 2016
• The Contribution of Cholesterol and its Metabolites to the Pathophysiology of Breast CancerAmy E. Baek, Erik R. Nelson — 2016
• ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancerJunjian Wang, June X. Zou, Xiaoqian Xue — 2016
• The sweet trap in tumors: aerobic glycolysis and potential targets for therapyLi Yu, Xun Chen, Liantang Wang — 2016
• Identification of functional metabolic biomarkers from lung cancer patient serum using PEP technologyZhenyu Sun, Xiaofeng Chen, Gan. Wang — 2016
• Pharmacological Targeting of a Metabolic Co-Dependency Pathway in Brain CancersG. Villa — 2016
• Application of Clinical BioinformaticsXiangdong Wang, Christian Baumgärtner, Denis C. Shields — 2016
• Fluorinated oxysterol analogues: Synthesis, molecular modelling and LXRβ activity.Cristian Rodríguez, Lautaro D. Álvarez, María V. Dansey — 2017
• Effect of GNP functionalisation and multiple N-methylation of β-amyloid residue (32-37) on Gram-positive bacterium.Nanjundaswamy Marishetty Hemmaragala, Heidi Abrahamse, Blassan P. George — 2017

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