Organ cooling in liver transplantation and resection: How low should we go?
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Summary
A new technique based on subzero nonfreezing preservation and extracorporeal machine perfusion is presented that allows transplantation of rat livers preserved for up to four days, thereby tripling the viable preservation duration.
- Type
- letter
- Published
- 2015-01-01
- Cited by
- 11
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W1516172679
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205895323
Keywords
Transplantation, Liver transplantation, Machine perfusion, Medicine, Extracorporeal
References
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- Controlled Oxygenated Rewarming of Cold Stored Liver Grafts by Thermally Graduated Machine Perfusion Prior to Reperfusion
- Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
- Reconstructive problems in canine liver homotransplantation with special reference to the postoperative role of hepatic venous flow.
- CRISPR — a widespread system that provides acquired resistance against phages in bacteria and archaea
- Targeted Mutagenesis in Zebrafish Using Customized Zinc Finger Nucleases
- Declining Liver Utilization for Transplant in the United States and the Impact of Donation after Cardiac Death
- Liver protection by hypothermic perfusion at different temperatures during total vascular exclusion
- CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
- Successful Supercooled Liver Storage for 4 Days
- Determination and Extension of the Limits to Static Cold Storage with Subnormothermic Machine Perfusion
- CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox.
- Adenoviral vector DNA for accurate genome editing with engineered nucleases
- Major Hepatic Resection Using Vascular Isolation and Hypothermic Perfusion
- Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
- In situ hypothermic perfusion with retrograde outflow during right hemihepatectomy: first experiences with a new technique.
- Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury.
- TALEN mediated somatic mutagenesis in murine models of cancer
- The sterile immune response during hepatic ischemia/reperfusion.
- Human embryonic stem cells commonly display large mitochondrial DNA deletions
Cited by
- Hypothermic Oxygenated Liver Perfusion: Basic Mechanisms and Clinical Application
- Hypothermic liver perfusion
- Protective Mechanisms of Hypothermia in Liver Surgery and Transplantation
- How much ischemia can the liver tolerate during resection?
- Enhancement of liver regeneration and liver surgery
- Hypo- and normothermic perfusion of the liver: Which way to go?
- Advances in hypothermic perfusion
- Enhancing Liver Transplant Outcomes through Liver Precooling to Mitigate Inflammatory Response and Protect Mitochondrial Function
- Enhancing Liver Transplant Outcomes Through Liver Precooling to Mitigate Inflammatory Response and Protect Mitochondrial Function
- Hepatic parenchymal transection increases liver volume but not function after portal vein embolization in rabbits
- Cooling Techniques and Ex Situ Liver Surgery
- Enhancement of liver regeneration and liver surgery
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