Targeted Mutagenesis in Zebrafish Using Customized Zinc Finger Nucleases
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Summary
Using these methods, zebrafish founders carrying targeted mutations can be identified within 4 months, and the vectors and methods are compatible with previously described Zinc-Finger Consortium reagents for constructing engineered zinc-finger arrays.
- Type
- article
- Published
- 2009-12-01
- Cited by
- 144
- References
- 45
- Access
- Open access
- OpenAlex
- https://openalex.org/W1965520671
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10336761
Keywords
Zinc finger nuclease, Zinc finger, Zebrafish, Mutagenesis, Biology
References
- The zebrafish book : a guide for the laboratory use of zebrafish (Danio rerio)
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- The use of zinc finger peptides to study the role of specific factor binding sites in the chromatin environment.
- Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification
- Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells
- Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases
- Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
- Human zinc fingers as building blocks in the construction of artificial transcription factors
- Precise genome modification in the crop species Zea mays using zinc-finger nucleases
- Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly
- Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells
- Gene targeting using zinc finger nucleases
- Design, construction and in vitro testing of zinc finger nucleases
- Highly efficient endogenous human gene correction using designed zinc-finger nucleases
- Efficient Gene Targeting in Drosophila With Zinc-Finger Nucleases
- Site-specific cleavage of DNA-RNA hybrids by zinc finger/FokI cleavage domain fusions.
- Custom-designed zinc finger nucleases: What is next?
- Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage.
- Enhancing Gene Targeting with Designed Zinc Finger Nucleases
Cited by
- Prion protein function and the disturbance of early embryonic development in zebrafish
- Generating Conditional Mutations in Zebrafish Using Gene-trap Mutagenesis
- Functional Roles of Syngap1 in Early Embryonic Development of Zebrafish
- Current Protocols in Molecular Biology Engineering Designer Transcription Activator-Like Effector Nucleases (TALENs)
- New Insights from Studying Insulin-like Growth Factor (IGF)-Binding Protein-5 in Zebrafish : Role of IGF Signaling in Epithelial Calcium Absorption.
- Dissection of cardiovascular development and disease pathways in zebrafish.
- Zebrafish as a Model for the Study of Parkinson’s Disease
- Dissecting the role of the ETV6 transcriptional regulator in development and disease
- Organ cooling in liver transplantation and resection: How low should we go?
- Cutting short the path to murine liver cancer models
- Quantifying Cardiac Functions in Embryonic and Adult Zebrafish
- Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein
- Dissecting mechanisms of myelinated axon formation using zebrafish.
- Analysis of the Retina in the Zebrafish Model
- Improving Zinc Finger Nucleases - Strategies for Increasing Gene Editing Activities and Evaluating Off-Target Effects
- Engineering nucleases for gene targeting: safety and regulatory considerations.
- Methods for targeted mutagenesis in zebrafish using TALENs
- Efficient In Vivo Genome Editing Using RNA-Guided Nucleases
- The comparative neuroanatomy and neurochemistry of zebrafish CNS systems of relevance to human neuropsychiatric diseases.
- Zinc-finger nuclease based genome surgery: it's all about specificity.
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